SCHOOL OF BIOLOGICAL SCIENCES
Undergraduate Courses in Biological Sciences
1A-B Life Sciences (4-4) F, W, S. Lecture, three hours. A two-quarter integrated sequence designed to introduce nonmajors to the basic concepts of modern biology. 1A: Discussion of evolutionary biology, ecology, molecular biology, and genetics. 1B: Cell and behavioral biology including plant structure and function, photosynthesis, and animal physiology. Prerequisite for 1B: Biological Sciences 1A. Open to nonmajors only. (II)
2A Freshman Seminars (1). Lecture, one hour; seminar, one hour. Weekly meetings consisting of presentations by faculty, professional staff, and New Student Peer Academic Advisors provide information about the School of Biological Sciences, campus resources, and special programs/opportunities. Pass/Not Pass only. Open to freshman Biological Sciences majors only.
2B Freshman Seminar (1). Seminar, one hour. Faculty presentations and readings focused on the structure, function, opportunities, and current issues in the biological sciences. Pass/Not Pass only. Open to freshmen only.
3A Career Decision Making (0). Lecture, one hour. An introductory course designed to facilitate the career decision-making process. Decision-making processes, values, and standardized tests of aptitudes, interests, and values are utilized with non-test data in appraising biological sciences career options. Pass/Not Pass only. One unit of workload credit only.
3B Non-Health Sciences Career Exploration (0). Lecture, one hour. A survey course designed to assist students in exploring non-health science career options. Lectures by professionals in various fields. Students are required to investigate one area of particular interest and do a career observation. Pass/Not Pass only. One unit of workload credit only. Open to sophomore, junior, or senior Biological Sciences majors only.
4 Introduction to Biomedical Research and Careers (0). Seminar, 1.5 hours. A seminar series for students interested in careers in the biological sciences and medicine. Presents a broad view of research areas, experimental approaches, clinical and industrial applications, issues of national health policies and economics, career paths in the biomedical sciences. May be repeated for credit as topics vary. One unit of workload credit only.
5 Introduction to Molecular Biology (4). Lecture, three hours. Molecules of life, with emphasis on medical applications. Open to nonmajors only. No credit given for Biological Sciences 5 if taken after Biological Sciences 99. (II)
6 Tropical Biology: Race to Save the Tropics (4). Lecture, three hours. Population growth combines with tropical resource consumption by industrialized nations to cause high rates of deforestation, pollution, habitat fragmentation, and extinction of species. Discusses tropical biomes, their population, community, and ecosystem processes, and possible means of conservation of biodiversity. (II)
7 Biostatistics (4) W, S. Lecture, three hours; discussion, one hour. Motivated by specific biological and medical issues, this course teaches introductory statistical techniques to investigate real-world experimental data from the health sciences, molecular, cellular, environmental, and evolutionary biology. Only one course from Biological Sciences 7, Mathematics 7/Statistics 7, or Management 7 may be taken for credit. No credit for Biological Sciences 7 if taken after Mathematics 67/Statistics 67. (V)
8A Human Genetics (4) S. Lecture, three hours; discussion, one hour. This survey course in human genetics includes an introduction to basic genetic concepts including family studies, chromosomes, molecular genetics of human disease, and an analysis of the Human Genome Project. Special emphasis is given to ethical and social issues. (II)
9A Nutrition Science (4) F, W. Lecture, three hours. An introduction to nutrition science, integrating concepts from biology, biochemistry, microbiology, physiology, and psychology to explain the interaction between nutrients and the human body. Biological basis of nutrient standards is analyzed. Effects of nutrition, behavior, exercises on health/disease. (II)
9B Biology and Chemistry of Food and Cooking (4) W. Lecture, three hours. The kitchen is used as a laboratory to introduce fundamental principles of biology, chemistry, and physics. A molecular/cellular analysis of cooking, including concepts such as protein structure, browning reactions, colloids, emulsions, carbohydrate metabolism, and development of flavor/texture through biochemical transformations. (II)
9C Biotech Basics (4). Lecture, three hours. An overview of current biotechnology. Discusses the biological/molecular basis of novel therapies for diseases, modification of human genes, human genome project, cloning, DNA fingerprinting, and genetically modified food. Targeted for students interested in modern breakthroughs in biology. (II)
9D Diseases of the Twenty-First Century (4) F. Lecture, three hours. Why do we get sick? An introduction to the biological basis of human disease, including diseases of the cardiovascular, respiratory, nervous, and reproductive systems. Case studies present diagnosis, treatment, and prevention protocols. Inheritable and infectious diseases also discussed. (II)
9E Horticulture Science (4). Lecture, two hours; laboratory, two hours; field work, one weekend day per quarter. Scientific principles of horticulture at the UCI Arboretum. Taxonomy, plant life history strategies; experiments with seed dormancy; morphological adaptations for specialized sexual and clonal reproduction; basics of plant propagation and ecological restoration. Laboratory fee. (II)
9F Current Issues in Biology: A Problem-Based Learning Approach (4). Seminar, three hours. Students explore in-depth several complex biological and interdisciplinary issues using problem-based learning. The main techniques for learning course material are group discussion, research, projects, and presentations. Attendance and group participation are mandatory. Prerequisites: Biological Sciences 1A-B or Biological Sciences 94 and 96. (II)
9G Way Your Body Works (4). Lecture, three hours. An introduction to the basic mechanisms that control the organ systems of the human body, including the nervous, cardiovascular, immune, and reproductive systems. Emphasis is on how the body works normally, but includes how these processes fail in disease. Open to nonmajors only. (II)
9J Biology of Oriental Medicine (4) W. Lecture, three hours. With lectures, demonstrations, and hands-on learning, the theory and practice of herbal medicine, acupuncture, qigong, and manipulative therapies are explained in Western biomedical terms. The latest basic and clinical research advances in each area are also described. Only one course from Biological Sciences 9J, 9H, and 9N may be taken for credit. (II)
9K Global-Change Biology (4) W. Lecture, three hours; discussion, one hour. Addresses ways in which humans are altering the global environment, with consequences for the ecology of animals, plants, and microbes. Discussion on how these biologically oriented questions relate to human society, politics, and the economy. Same as Earth System Science 13. (II)
9M The Biosphere (4) W. Lecture, three hours; discussion, one hour. An introduction to the role of biological processes in the Earth system. Topics span the functioning of cells, organisms, ecosystems, and the global biosphere, including an introduction to evolution, terrestrial and marine organismal biology, and principles of ecology and biogeochemistry. Same as Earth System Science 9. (II)
9N Introduction to Complementary and Alternative Medicine (4) Summer. Lecture, three hours. Basic and clinical research on complementary and alternative therapies (e.g., herbal medicine, mind-body practices, energy medicine, acupuncture, homeopathy, chiropractic, Ayurveda), and how such practices are integrated into Western medicine are discussed. Includes lectures, demonstrations, and hands-on learning. Only one course from Biological Sciences 9N, 9J, and 9H may be taken for credit. (II)
10 The Biology of Human Diseases (4). Lecture, three hours. Introduction to concepts of diagnosis, treatment, and prevention of major human infectious diseases. Covers some aspects of epidemiology. Scope and impact of infectious diseases in the present and past experiences in controlling infectious disease. Reviews the biology of human organ systems. Open to nonmajors only. (II)
11 Topics in Biological Sciences (4) F, W, S. Lecture, four hours. Studies in selected areas of biological sciences. May be taken for credit three times as topics vary. (II)
12A Human Reproduction and Development (4). Lecture, three hours. Provides detailed insight into human reproduction and development. Reproductive topics include anatomy/physiology of the adult reproductive systems, infertility, and STDs. Development topics include gamete formation, fertilization, fetal development, and birth. Human genetic diseases and developmental disorders also discussed. (II)
12C Neurobiology of Behavior (4). Lecture, three hours. Examines how animals ranging from insects to mammals have evolved neural solutions to specific problems posed by their environments. Principles derived from research findings draw on the fields of animal behavior, cellular physiology, anatomy, genetics, and molecular biology. (II)
12D Molecular Basis of Human Disease (4). Lecture, three hours; discussion, one hour. Introduction to the concepts of the cellular and molecular basis, treatment, and diagnosis of human disease. Diseases resulting from infectious agents such as virus, bacteria, protozoan and metazoan animals, and diseases resulting from genetic disorders discussed in context of molecular mechanisms. (II)
14 California Teach 1: Introduction to Science and Mathematics Teaching (2) W, S. Seminar, 1.5 hours; field work, 1.5 hours. First in a series for students interested in becoming middle or high school teachers of mathematics or science. Meets five times for students to gain an understanding of effective, research-based teaching strategies. Includes an opportunity to experience math and science teaching in a grade K-5 classroom. Prerequisite: freshman, sophomore, or junior standing or consent of instructor. Same as Physical Sciences 5.
15 Botany (4) F. Lecture, three hours. Structure and function of flowering plants related to their roles in ecology and human needs. (II)
16 Introduction to Darwinian Biology (4) W. Lecture, three hours. An introduction to the basic concepts of ecology, evolution, and functional biology suitable for non-scientists. Open to nonmajors only. No credit given for Biological Sciences 16 if taken after Biological Sciences E106. (II)
20 California Natural History (4) F. Lecture, three hours. Introduction to ecological relationships within a variety of California habitats. Explores aspects of the physical environments and the adaptations of organisms to their physical and biological surroundings in habitats such as the coastal zone, mountains, and deserts. (II)
25 Biology of Cancer (4) W. Lecture, four hours. Biological, clinical, and psychosocial nature of cancer through the perspectives of medical researchers, biologists, physicians, and health educators. For students of all majors, designed so that each can increase personal awareness of the biology of cancer.
30 Biomedical Ethics (4) S. Lecture, three hours. Ethical issues inherent in twenty-first-century biological and medical advances. An introduction to the basic biology underlying these issues and an analysis of the ethical implications to society. Topics such as cloning, stem cell research, genetic engineering are discussed by guest speakers.
35 The Brain and Behavior (4). Lecture, three hours. Introduction to how the brain works. Biological processes underlying perception, movement, sleep-wake cycles, motivation, language, learning, and memory. Changes in the brain associated with sex differences, drug use, aging, seasons, and time of day. Fundamental properties of the nervous system. Open to nonmajors only. (II)
36 Drugs and the Brain (4). Lecture, three hours. Introduction to the actions of drugs on the brain. How studying drug action helps to reveal normal functions of neurons. How drugs can correct neural disorders or disrupt neural function. Biological issues related to drug abuse, drug addiction, and drug seeking. Open to nonmajors only. (II)
37 Brain Dysfunction and Repair (4). Lecture, three hours. Introduction to the disruptions in brain function that underlie disorders such as Alzheimer's disease, Parkinsonism, schizophrenia, and depression, and the basis for drug therapies. The brain's ability to repair itself after damage and the pros and cons of that repair. Open to nonmajors only. (II)
38 Mind, Memory, Amnesia, and the Brain (4) S. Lecture, three hours. Introduction to neural mechanisms underlying learning and memory. Emphasis on molecular changes that mediate memory as well as structures involved in different forms of memory. Additionally, the biology of memory phenomena, from extraordinary memory to false memory to amnesia is examined. Open to nonmajors only. (II)
45 AIDS Fundamentals (4) F, W. Lecture, three hours; discussion, one hour. Considers the biological and sociological bases of the AIDS epidemic. Topics include the history of AIDS, current medical knowledge, transmission, risk reduction, and how the community can respond. Same as Planning, Policy, and Design 45 and Public Health 80. (II)
46 Discussion and Literature Research in AIDS (2 to 4) F, W. Discussion, two hours; research, two hours. Students carry out two activities: (1) leading discussions about HIV/AIDS (predominantly regarding sociological and personal reactions) among students taking the AIDS Fundamentals course and (2) literature research about biomedical aspects of AIDS. Prerequisite: Biological Sciences 45 or Planning, Policy, and Design 45 or Public Health 80; consent of instructor.
50 Biology of Heart Disease (4) S. Lecture, four hours. Guest lecturers from the field of cardiovascular medicine discuss current concepts regarding cause, diagnosis, and treatment of heart disease. Topics include surgery, rehabilitation, and congenital defects, with emphasis on prevention.
55 Introduction to Ecology (4). Lecture, three hours. Principles of ecology; application to populations, communities, ecosystems, and humans. Open to nonmajors only. No credit given for Biological Sciences 55 if taken after Biological Sciences 96 or E106. (II)
65 Biodiversity and Conservation (4) W. Lecture, three hours. A biological perspective on the current environmental crisis. The origin, evolution, and value of biological diversity. Extinction and depletion caused by overexploitation, habitat loss, and pollution. Conservation through habitat preservation and restoration, captive breeding, cryopreservation. (II)
75 Human Development: Conception to Birth (4) W, S. Lecture, three hours. Processes leading to the birth of a healthy child and the avoidance of birth defects. Male and female reproductive systems, hormonal control of egg-sperm formations, sexual intercourse, contraception, venereal diseases, fertilization, cell division, embryonic development, fetal physiology. Open to nonmajors only. (II)
H90 The Idiom and Practice of Science (4). The importance of biological sciences in our world are discussed. Topics may include brain and behavior, health and disease, genetics and society, and conservation biology. A primary goal is to encourage students to understand better the world in which they live. Prerequisite: restricted to members of the Campuswide Honors Program. (II)
92 Special Group Activities
Sec. 3 Reading, Writing, and Reasoning for Health Science (4) F, W, S. Designed to strengthen biology students' reading, writing, and critical thinking skills to ensure their success at the University and to prepare them for graduate study in medicine, dentistry, optometry, or public health. Pass/Not Pass only. Open to Biological Sciences majors only.
Sec. 5 Curriculum (2). Initiation, planning, and coordination of student-run courses. Prerequisite: consent of instructor. May be repeated for a total of eight units. Pass/Not Pass only.
101 California Teach 2: Middle School Science and Mathematics Teaching (2) F, W. Seminar, 1.5 hours; field work, 1.5 hours. Second in a series for students interested in becoming middle or high school teachers of mathematics or science. Meets five times for students to gain an understanding of effective, research-based teaching strategies. Includes an opportunity to experience teaching in a grade 6-8 classroom. Prerequisite: Biological Sciences 14. Same as Physical Sciences 105.
102 California Teach 3: High School Science and Mathematics Teaching (2) F, W. Seminar, 1.5 hours; field work, 1.5 hours. Capstone of a series of three seminars for students interested in becoming secondary mathematics or science teachers. Meets six times for students to understand effective, research-based teaching strategies. Includes an opportunity to experience teaching in a high school. Prerequisites: Biological Sciences 14 and 101. Same as Physical Sciences 106.
190 Transfer Student Seminars (1). Lecture, one hour; seminar, one hour. Weekly meetings consisting of presentations by faculty, professional staff, and New Student Peer Academic Advisors provide information about the School of Biological Sciences, campus resources, and special programs/ opportunities. Pass/Not Pass only. Open to new transfer students only.
CORE CURRICULUM
Prerequisites listed for Core courses are rigorously enforced. (Transfer students who have successfully completed one or more years of college biology should consult with the Biological Sciences Student Affairs Office for possible exemption from portions of the Core.)
93 From DNA to Organisms (4) F. Lecture, three hours; discussion, one hour. Cell biology, biochemistry, genetics, and the biology of organ systems. Covers concepts of building blocks (nucleotides, amino acids, and cells) and of information flow (DNA to proteins, receptors to nuclei, the blood to distant organs, and DNA to offspring). No credit given for Biological Sciences 93 if taken after Biological Sciences 97 and/or 98. (II)
94 From Organisms to Ecosystems (4) W. Lecture, three hours; discussion, one hour. Patterns of diversity, ecology, and evolutionary biology. Emphasis is on the Tree of Life and how its members are distributed and interact. Prerequisite: Biological Sciences 93. No credit given for Biological Sciences 1A if taken after Biological Sciences 94. (II)
97 Genetics (4) F. Lecture, three hours; discussion, one hour. Introduction to genetics. Basic features of the replication and expression of DNA; cell division; and gene transmission. Recombination and mutation in diploid organisms. Prerequisite: Biological Sciences 94.
98 Biochemistry (4) W. Lecture, three hours. Structure and properties of proteins; major biochemical pathways and mechanisms for their control. Prerequisites: completion of Biological Sciences 97 and completion of or concurrent enrollment in Chemistry 51B or 52B.
99 Molecular Biology (4) S. Lecture, three hours. Biochemistry and replication of nucleic acids; molecular genetics; protein biosynthesis; genetic code; regulation of expression of genetic information; biochemical evolution. Prerequisite: Biological Sciences 98.
100L Experimental Biology Laboratory (4) F, S. Lecture, one hour; laboratory, three hours. Basic experimental design, laboratory techniques, data gathering skills, and analysis and preservation of data for a variety of areas of inquiry in the biological sciences. Prerequisites: current enrollment in or completion of Biological Sciences 97 and 194S; satisfactory completion of the lower-division writing requirement.
D103 Cell Biology (4) F, W. Lecture, three hours; discussion, one hour. Analysis of the basic structure and function of animal cells, with an emphasis on the regulation of cellular processes. The basic features of membranes, cellular compartmentalization, protein trafficking, vesicular transport, cytoskeleton, adhesion, signal transduction, and cell cycle are covered. Prerequisite: Biological Sciences 99. Biological Sciences D103 and 107 may not both be taken for credit. Formerly Biological Sciences 103.
D104 Developmental Biology (4) F, W. Lecture, three hours; discussion, one hour. Cellular and molecular analysis of how a fertilized egg develops into an organism consisting of complex structures such as the eye, arms, and brain. Emphasis is on the key concepts of developmental processes underlying pattern formation, growth, and regeneration. Corequisite or prerequisite: Biological Sciences D103. Biological Sciences D104 and 108 may not both be taken for credit. Formerly Biological Sciences 104.
D105 Cell, Developmental, and Molecular Biology of Plants (4) F. Lecture, three hours. Emphasizes the special features of plant cells and plant development as compared to animals. Plants' ability to fuel our planet through photosynthesis and the interactions of plants with microorganisms in making nitrogen available to other life forms are two central topics. Prerequisite: Biological Sciences 99. Formerly Biological Sciences 105.
E106 Processes in Ecology and Evolution (4) S. Lecture, three hours; discussion, one hour. An in-depth study of the mechanisms that drive evolution and ecology including: natural selection, mutation, genetic drift, speciation, extinction, life history patterns, population dynamics, ecosystem and community structure, predator-prey and host pathogen interactions, and social behavior. Prerequisite: Biological Sciences 93. May be used as a course repeat of Biological Sciences 96. Biological Sciences E106 and 96 may not both be taken for credit. Formerly Biological Sciences 106.
E109 Human Physiology (4) F, W. Lecture, three hours. Functional features of the major organ systems in the human body. Emphasis on homeostasis and the interactions of organ systems in health and disease. (Discussion of behavior and brain function deferred to Biological Sciences N110.) Prerequisite: Biological Sciences 99. Formerly Biological Sciences 109.
N110 Neurobiology and Behavior (4) S. Lecture, three hours. Consideration of the evolution of behavior, including ethological and psychological aspects and analysis of neuroanatomical, neurochemical, neurophysiological, and neuroendocrine systems underlying basic behavioral processes. Corequisite or prerequisite: Biological Sciences 99. Formerly Biological Sciences 110.
UPPER-DIVISION LABORATORIES
D111L Developmental and Cell Biology Laboratory (3) F, W, S. Laboratory, four hours. Students study the division of cells, isolate cellular organelles (chloroplasts, mitochondria, nuclei), and follow changes in cells undergoing programmed cell death. Development is demonstrated in experiments showing cooperation of individual cells in forming a multicellular organism. Prerequisites: Biological Sciences 100L and 194S; concurrent enrollment in or completion of Biological Sciences D103 or D104 or D105. Formerly Biological Sciences 111L.
E112L Physiology Laboratory (3) F, W, S. Laboratory, four hours. Prerequisites: Biological Sciences 100L, E109, and 194S. Formerly Biological Sciences 112L.
E115L Evolution Laboratory (4) S. Laboratory, seven hours. Students perform experiments which illustrate important concepts in evolutionary biology such as natural selection, random genetic drift, inbreeding, age-specific selection, sexual selection, and phylogenetic reconstruction. Prerequisites: Biological Sciences 100L, E106, and 194S. Formerly Biological Sciences 115L.
E166 Field Methods in Ecology (6) F. Laboratory, eight hours. Field studies of major concepts in plant and animal ecology, with emphasis on experimental design, field sampling methods, statistical analysis, and scientific writing. An independent project and two weekend camping trips are required. Satisfies the upper-division writing requirement with a grade of C or better. Prerequisites: Biological Sciences 100L, E106, and 194S, and satisfactory completion of the lower-division writing requirement. Formerly Biological Sciences 166.
M114L Biochemistry Laboratory (4) F, W, S. Laboratory, four hours. Properties of enzymes and the culture and isolation of mutants of microorganisms. Prerequisites: Biological Sciences 99, 100L, and 194S. Formerly Biological Sciences 114L.
M116L Molecular Biology Laboratory (4) F, W, S, Summer. Laboratory, four hours. Students perform experiments which illustrate the chemical and biological properties of nucleic acids. Emphasis is placed on recent techniques in recombinant DNA technology including gene isolation and characterization. Prerequisites: Biological Sciences 99, 100L, and 194S. Formerly Biological Sciences 116L.
M118L Experimental Microbiology Laboratory (3) F, W, S, Summer. Laboratory, three hours. Introductory general microbiology designed for preprofessional biology majors. Includes microscopy, cultivation of bacteria, morphological and biochemical characterization of bacteria, microbial metabolism, growth and genetics, microorganisms and human disease, and interactions of microorganisms with the environment. Prerequisites: Biological Sciences 100L and 194S; concurrent enrollment in or completion of Biological Sciences M122 or M132, or equivalent. M118L and M122L may not both be taken for credit.
M121L Advanced Immunology Laboratory (4) S. Laboratory, four hours. Emphasis is placed on learning modern techniques in immunology such as ELISAs, western blotting, immunofluorescent staining assays. Prerequisites: Biological Sciences M116L and M121; consent of instructor. Concurrent with Molecular Biology and Biochemistry 221L. Formerly Biological Sciences 121L.
M122L General Microbiology Laboratory (6) F, Summer. Laboratory, six hours. Selective isolation of wide variety of microbial types. Characterization and identification by morphological and comparative nutritional and biochemical approaches. Industrial, medical, and biological research applications. Prerequisites: Biological Sciences 100L and 194S; concurrent enrollment in or completion of Biological Sciences M122 or M132, or equivalent. Formerly Biological Sciences 122L. M122L and M118L may not both be taken for credit.
M124L Virus Engineering Laboratory (4) S. Laboratory, four hours; discussion, one hour. An advanced laboratory for undergraduates who have completed a virology lecture class. Students learn to engineer recombinant viruses and express genes in mouse tissue. Prerequisites: Biological Sciences M116L and M124A or M124B; consent of instructor. Formerly Biological Sciences 124L.
N113L Neurobiology Laboratory (3) W, S. Laboratory, four hours. Prerequisites: Biological Sciences 100L and 194S; concurrent enrollment in or completion of Biological Sciences N110. Formerly Biological Sciences 113L.
UPPER-DIVISION ELECTIVES
DEVELOPMENTAL AND CELL BIOLOGY
D113 Genetics Majors Seminar (1) W. Seminar, one hour. Genetics majors attend a weekly seminar to discuss current research techniques and career opportunities in the field. Students have the opportunity to present their own independent research. Open to Genetics majors only. May be taken for credit two times.
D114 Developmental and Cell Biology Majors Seminar (1) S. Seminar, one hour. Developmental and Cell Biology majors attend a weekly seminar to discuss current research techniques and career opportunities in the field. Students have the opportunity to present their own independent research. Open to Developmental and Cell Biology majors only. May be taken for credit two times.
D115 Molecular Motors and the Cytoskeleton (4). Lecture, three hours; discussion, one hour. Cells use nano-machines (molecular motors) to organize themselves and transport cargo. This interdisciplinary course studies these motors and the rails they move along. Examines their biological function and how they function at the single-molecule level as machines. Prerequisite: Biological Sciences D103 or consent of instructor. Concurrent with Developmental and Cell Biology 205. Formerly Biological Sciences 115.
D126 Systems Biology of Human Disorders (4) F, W, S. Lecture, three hours; discussion, one hour. Introduces human pathophysiology using a systems biology perspective. Focuses on the proper regulation of human systems, and the dire consequences of loss of regulation. The goal is to impart an "engineering" mind-set to understand human disorders. Prerequisites: Biological Sciences 99 or Engineering BME50A-B and Mathematics 2A-B. Formerly Biological Sciences 126A.
D129 Biotechnology and Plant Breeding (4) F. Lecture, three hours. Synopsis of conventional plant breeding techniques, their limitations, and supplementations through modern biotechnology. These new biotechnological methods include steps such as cloning, cell transformation (genetic engineering), and cell fusion. Focuses on crop improvement, the state of the art in animal and human systems, and the impact of gene technology on society. Prerequisite: Biological Sciences 94 or consent of instructor. Formerly Biological Sciences 129.
D129L Plant Cell Culture Laboratory (4) W of odd years. Laboratory, 60 hours per quarter, run on two, full three-day weekend sessions which normally will not conflict with other classes. Isolation and culture of plant cells and tissues, i.e., protoplasts, pollen, meristem. Genetics and structural manipulation of cultured cells, i.e., fusion, laser microsurgery, mutation. Regeneration of plants from cultured cells and tissues. Greenhouse experience (propagation, fertilization, grafting). Prerequisite: Biological Sciences D129 or consent of instructor. Formerly Biological Sciences 129L.
D130 Photomedicine (4) W. Lecture, three hours; discussion, one hour. Studies the use of optical and engineering-based systems (laser-based) for diagnosis, treating diseases, manipulation of cells and cell function. Physical, optical, and electro-optical principles are explored regarding molecular, cellular, organ, and organism applications. Prerequisites: Physics 3A-B-C or 7A-B-D, or Engineering EECS12, or consent of instructor. Same as Engineering BME135. Formerly Biological Sciences 130.
D134 Plant Physiology (4) S. Lecture, three hours. Plant hormones, growth and development, metabolism, mineral nutrition, and photosynthesis. Prerequisite: Biological Sciences 15 or consent of instructor. Formerly Biological Sciences 134.
D136 Human Anatomy (4) F, W, S. Lecture, three hours; discussion, one hour. Presents a systems approach to the analysis of human structure. Molecular, cellular, tissue, organ, and organ system levels of structure and organization are integrated throughout. Prerequisite: Biological Sciences 99. Formerly Biological Sciences 136A.
D137 Eukaryotic and Human Genetics (4) F. Lecture, four hours. Structure and function of genes in eukaryotes with emphasis on special problems of genetic studies in humans. Molecular methods of genetic analysis and gene transfer are discussed. Practical applications and ethical and social issues raised by genetic studies are addressed. Prerequisites: Biological Sciences 97; Biological Sciences 99 recommended. Formerly Biological Sciences 137B.
D145 Genomics and Proteomics (4) W. Lecture, three hours. Focuses on the applications of genomics and proteomics to problems in genetics, cell, and developmental biology. Students gain a comprehensive understanding of the techniques currently used for genomics analysis and how best to apply these tools to solve research problems. Prerequisites: Biological Sciences 97, 98, 99. Formerly Biological Sciences 145B.
D146 Eukaryotic Genes (4) W. Lecture, three hours. Molecular organization of eukaryotic genes and the molecular mechanisms which regulate their expression. Topics include developmentally regulated genes, tissue-specific gene expression, multigene families, oncogenes, gene transposition, and recombinant gene cloning. Prerequisite: Biological Sciences 99. Formerly Biological Sciences 145A.
D147 Plant Molecular Biology (4) W. Lecture, three hours. Presents the molecular mechanisms of plant growth and development. Topics considered include: the identification of genes regulating cell division, growth, and morphogenesis; control of gene expression by external and internal factors; plant transformation mechanisms. Prerequisite: Biological Sciences D105. Formerly Biological Sciences 147.
D148 Development and Disease (4) S. Lecture, three hours. Development of animal embryos from a fertilized egg to a functioning organism. Topics include body-axis formation, growth and differentiation of embryonic cells, and organogenesis, with an emphasis on congenital birth defects and diseases that disrupt these processes. Prerequisite: Biological Sciences D104. Formerly Biological Sciences 148.
D149 Development, Injury, and Repair of the Nervous System (4) F, W. Lecture, three hours. The formation of the nervous system including neurogenesis, trophic factors, cell death, and formation of nerve connections. Damage to the brain and spinal cord from injury and disease and experimental strategies for repair. Prerequisite: Biological Sciences N110. Formerly Biological Sciences 149.
D151 Advanced Cell Biology (4) W. Lecture, four hours. Plasma membrane and cytoskeletal-mediated events. Topics include: endocytosis, receptor-ligand interactions, the biochemical basis of growth control, cell structure and motility, and cell-cell, cell matrix interactions. The biochemistry and molecular aspects of these topics are emphasized. Prerequisite: Biological Sciences D103. Formerly Biological Sciences 144B.
D153 Molecular and Cellular Basics of Disease (4) W. Lecture, three hours. Provides students with examples of how human disease is usually manifested at the cellular level. The roles of specific molecules and organelles are discussed where their roles in the disease process are understood. Prerequisite: Biological Sciences D103. Formerly Biological Sciences 144D.
D154 Developmental and Cell Biology (4) W. Lecture, three hours. An advanced, integrated view of cell biology. Topics include the cell cycle, the cytoskeleton, the extracellular matrix, signal transduction, the cellular basis of development, and the cell biology of cancer. Prerequisite: Biological Sciences D103 or 107. Concurrent with Developmental and Cell Biology 231B. Formerly Biological Sciences 144E.
D180 Fractal Geometry in Biology (4) F. Lecture, two hours; discussion, one hour. Fractal geometry explored with tools and interests of the biologist. Provides a general background of fractal geometry and investigates the types of biological processes that generate fractals. Prerequisites: completion of the Biological Sciences Core, Physics 3A, and Mathematics 2B. Formerly Biological Sciences 180.
D187 Developmental Genetics (4) W of odd years. Lecture, three hours. Advanced course on the use of genetic analysis to identify the genes that control cell behavior and development. Instructor-led discussion of genetics and the relationship between genotype and phenotype followed by student-led discussion based on assigned readings. Prerequisite: Biological Sciences D137. Formerly Biological Sciences 187.
D190 Topics in Developmental and Cell Biology (2 to 4) F, W, S. Lecture, two hours. Studies in selected areas of developmental and cell biology. Prerequisites: Biological Sciences D103; limited to School of Biological Sciences majors with upper-division standing. May be taken for credit three times as topics vary. Formerly Biological Sciences 139.