Courses in Chemistry
LOWER-DIVISION
NOTE: Enrollment in lower-division Chemistry courses may be subject to pre-testing or other limitations. See the Catalogue's Placement Testing section and the Schedule of Classes (available at http://www.reg.uci.edu) for information.
1A-B-C General Chemistry (4-4-4) F, W, S, Summer. Lecture, three hours; discussion, one hour. Atomic and molecular structure; properties of gases, liquids, solids, and solutions; stoichiometry; chemical equilibrium; chemical thermodynamics; chemical kinetics; periodic properties and descriptive chemistry of the elements. Corequisite: concurrent enrollment in the corresponding laboratory courses. Prerequisite for Chemistry 1A: high school chemistry and one of the following: a passing score on the UCI Chemistry Placement Examination or a grade of C or better in Chemistry 1P; for Chemistry 1B and 1C, a grade of C- or better in all previous courses in the sequence. Chemistry 1A-B-C and Chemistry H2A-B-C may not both be taken for credit. (II) NOTE: The Chemistry Placement Examination, which is to be taken prior to enrollment in Chemistry 1A, assesses the student's preparation for General Chemistry. The Chemistry Department does not accept preparatory courses from other academic institutions in lieu of the Chemistry Placement Examination. Students enrolled in the W-S-Summer/F sequence of Chemistry 1A-B-C must complete Chemistry 1C in the Summer Session to be eligible to enroll in Chemistry 51A or H52A in the subsequent fall quarter.
1LB-LC General Chemistry Laboratory (2-2) F, W, S, Summer. Discussion, one hour; laboratory, four hours. Training and experience in basic laboratory techniques. Chemical practice and principles illustrated through experiments related to lecture topics in Chemistry 1A-B-C. Corequisite for Chemistry 1LB and 1LC: concurrent enrollment in the corresponding segment of Chemistry 1. Prerequisite for Chemistry 1LB: a grade of C- or better in Chemistry 1A or Chemistry 1A and 1LA. Prerequisite for Chemistry 1LC: a grade of C- or better in Chemistry 1B and 1LB. Chemistry 1LB-LC and H2LB-LC may not both be taken for credit. Only one course from Chemistry 1LB, 1LE, H2LB, and M2LB may be taken for credit. (IX)
1LE Accelerated General Chemistry Laboratory (3) F, W, Summer. Discussion, two hours; laboratory, four hours. Lecture and experiments covering chemical concepts for accelerated students who do not plan to take organic chemistry. Properties of gases, liquids, solutions, and solids; chemical equilibrium, chemical thermodynamics; atomic and molecular structure; chemical kinetics; electrochemistry. Corequisite: Chemistry 1A or 1B. Prerequisite: Chemistry placement examination or a grade of C or better in Chemistry 1P. Only one course from Chemistry 1LE, 1LB, H2LB, and M2LB may be taken for credit. (IX)
1P Preparation for General Chemistry (4) F, W, Summer. Lecture, three hours; quiz, two hours. Units of measurement, dimensional analysis, significant figures; elementary concepts of volume, mass, force, pressure, energy, density, temperature, heat, work; fundamentals of atomic and molecular structure; the mole concept; stoichiometry; properties of the states of matter; gas laws; solutions, concentrations. Prerequisite: Chemistry placement examination for fall and winter enrollment. NOTE: Chemistry 1P satisfies no requirements other than contribution to the 180 units required for graduation. Designed for students who need additional help prior to enrollment in General Chemistry.
H2A-B-C Honors General Chemistry (4-4-4) F, W, S. Lecture, three hours; discussion, one hour. Covers the same material as Chemistry 1A-B-C but in greater depth. Additional topics included as time permits. Corequisite: concurrent enrollment in the corresponding quarter of Chemistry H2LA-LB-LC. Prerequisite for H2A: membership in the Campuswide Honors Program, or a score of 4 or 5 on the Chemistry Advanced Placement Examination, or a score of 700 or better on the SAT II in Chemistry, or a qualifying score on the UCI Chemistry Placement Examination, or consent of instructor. Prerequisite for H2B-H2C: grade of B or better in preceding course in series. Chemistry H2A-B-C satisfies the same requirements and prerequisites as Chemistry 1A-B-C; corresponding segments may not both be taken for credit. (II)
H2LA-LB-LC Honors General Chemistry Laboratory (2-2-2) F, W, S. Laboratory, three hours (H2LA), four hours (H2LB-LC). Training and experience in basic laboratory techniques through experiments related to lecture topics in Chemistry H2A-B-C. Corequisite: concurrent enrollment in the corresponding segment of Chemistry H2A-B-C. Prerequisites: membership in the Campuswide Honors Program, or a score of 4 or 5 on the Chemistry Advanced Placement Examination, or a score of 700 or better on the SAT II in Chemistry, or a qualifying score on the UCI Chemistry Placement Examination, or consent of instructor. Chemistry H2LA-LB-LC and Chemistry 1LA-LB-LC may not both be taken for credit. Only one course from Chemistry H2LB, M2LB, 1LB, and ILE may be taken for credit. (IX)
M2LA-LB-LC Majors General Chemistry Laboratory (2-2-2) F, W, S. Discussion, one hour; laboratory, four hours. Training and experience in basic laboratory techniques through experiments related to lecture topics in Chemistry 1A-B-C. Corequisite: concurrent enrollment in the corresponding segment of Chemistry 1A-B-C. Prerequisite: Chemistry Placement Examination or a grade of C or better in Chemistry 1P. Open to Chemistry majors only. Chemistry M2LA-LB-LC and Chemistry 1LA-LB-LC may not both be taken for credit. (IX)
5 Scientific Computing Skills (4) F, S, Summer. Lecture, three hours; discussion, one hour; laboratory, two hours. Introduces students to the personal computing software used by chemists for managing and processing of data sets, plotting of graphs, symbolic and numerical manipulation of mathematical equations, and representing chemical reactions and chemical formulas. Corequisites: Chemistry 1C or H2C, and Mathematics 2D. Prerequisites: Chemistry 1A-B or H2A-B, and Mathematics 2A-B.
51A-B-C Organic Chemistry (4-4-4); 51A (F, W, Summer), 51B (W, S, Summer), 51C (S, Summer, F). Lecture, three hours; discussion, one hour. Fundamental concepts relating to carbon compounds with emphasis on structural theory and the nature of chemical bonding, stereochemistry, reaction mechanisms, and spectroscopic, physical, and chemical properties of the principal classes of carbon compounds. Corequisite for 51A-B: concurrent enrollment in the corresponding segment of Chemistry 51L. Prerequisites for 51A: Chemistry 1A-B-C and 1LB-1LC. Prerequisites for 51B and 51C: a grade of C- or better in previous quarter of sequence. Chemistry 51A-B-C and Chemistry H52A-B-C may not both be taken for credit.NOTE: Priority for enrollment in the Chemistry 51A-B-C sequence offered in W-S-Summer/F is given to students who successfully complete Chemistry 1C in the preceding fall quarter.
51LA-LB-LC Organic Chemistry Laboratory (2-2-2); 51LA (F, W, Summer), 51LB (W, S, Summer), 51LC (S, Summer, F). Discussion, one hour; laboratory, four hours. Modern techniques of organic chemistry, using selected experiments to illustrate topics introduced in Chemistry 51A-B-C. Corequisite for 51LA-LB-LC: concurrent enrollment in the corresponding segment of Chemistry 51. Prerequisites for 51LB: a grade of C- or better in Chemistry 51A and 51LA. Prerequisites for 51LC: a grade of C- or better in Chemistry 51B and 51LB. Chemistry 51LA-LB-LC and Chemistry H52LA-LB-LC may not both be taken for credit.NOTE: Chemistry H52A-B-C, H52LA-LB-LC satisfy the same requirements and prerequisites as Chemistry 51A-B-C, 51LA-LB-LC; corresponding segments may not both be taken for credit.
H52A-B-C Honors Organic Chemistry (4-4-4) F, W, S. Lecture, three hours; discussion, one hour. Fundamental concepts of the chemistry of carbon compounds. Structural, physical, and chemical properties of the principal classes of carbon compounds. Corequisite: concurrent enrollment in the corresponding segment of Chemistry H52L. Prerequisites for H52A: a B average in Chemistry 1A-B-C or H2A-B-C or consent of instructor. Prerequisites for H52B and H52C: a grade of C or better in previous quarter of sequence. Chemistry H52A-B-C and Chemistry 51A-B-C may not both be taken for credit.
H52LA-LB-LC Honors Organic Chemistry Laboratory (2-2-2) F, W, S. Laboratory, five hours. Fundamental techniques of modern experimental organic chemistry. Corequisite: concurrent enrollment in the corresponding segment of Chemistry H52. Prerequisite for H52LB and H52LC: a grade of C or better in previous quarter of sequence. Chemistry H52LA-LB-LC and Chemistry 51LA-LB-LC may not both be taken for credit.
H90 The Idiom and Practice of Science (4). Lecture, three hours; discussion, two hours. A series of fundamental and applied scientific problems are addressed, illustrating the pervasive role of mathematical analysis. Topics may include thermodynamics, chemical equilibria, acid-base chemistry, kinetics, states of matter, electronic structure of atoms and the periodic table, chemical bonding, spectroscopy, and topics from organic, atmospheric, and biochemistry. Open only to members of the Campuswide Honors Program or consent of instructor. (II)
UPPER-DIVISION
107 Inorganic Chemistry I (4) W. Lecture, three hours; discussion, one hour. Introduction to modern inorganic chemistry. Principles of structure, bonding, and chemical reactivity with application to compounds of the main group and transition elements, including organometallic chemistry. Prerequisites: Chemistry 1A-B-C; 51A-B-C or H52A-B-C.
107L Inorganic Chemistry Laboratory (3) S. Laboratory, seven hours; discussion, one hour. Modern techniques of inorganic and organometallic chemistry including experience with glove box, Schlenk line, and vacuum line methods. Prerequisite: Chemistry 107.
125 Advanced Organic Chemistry (4) F. Lecture, three hours; discussion, one hour. Rapid-paced comprehensive treatment of organic chemistry, reinforcing the fundamental concepts introduced in Chemistry 51A-B-C and H52A-B-C. Focuses on molecular structure, reactivity, stability, scope and mechanisms of organic reactions. Topics include: structure and bonding; theoretical organic chemistry; acidity and basicity; reactive intermediates; pericyclic reactions; stereochemistry; organic synthesis; natural products; organic photochemistry. Prerequisites: Chemistry 51A-B-C or H52A-B-C.
127 Inorganic Chemistry II (4) S. Lecture, three hours; discussion, one hour. Advanced treatment of selected fundamental topics in inorganic chemistry, building on material presented in Chemistry 107. Molecular symmetry with applications to electronic structure and spectroscopy. Reaction kinetics and mechanisms; inorganic synthesis and catalysis; bioinorganic chemistry. Prerequisite: Chemistry 107.
128 Introduction to Chemical Biology (4) W. Lecture, three hours; discussion, one hour. Introduction to the basic principles of chemical biology: structures and reactivity; chemical mechanisms of enzyme catalysis; chemistry of signaling, biosynthesis, and metabolic pathways. Prerequisites: Chemistry 1A-B-C; Chemistry 51A-B-C or H52A-B-C.
128L Introduction to Chemical Biology Laboratory Techniques (4) S. Discussion, one hour; laboratory, six hours. Introduction to the basic laboratory techniques of chemical biology: electrophoresis, plasmid preparation, PCR, protein expression, isolation, and kinetics. Prerequisite: Chemistry 128.
NOTE: Chemistry 130A-B-C and 131A-B-C are parallel courses in physical chemistry; both are acceptable to satisfy the physical chemistry requirements for the major. Because of significant differences in course content, students starting in one series may not switch to the other in subsequent quarters.
130A-B-C Physical Chemistry: Biological and Materials Applications. Lecture, three hours; discussion, one hour.
130A Chemical Thermodynamics (4) F. Principles of chemical and heterogeneous equilibrium. Multiple chemical equilibrium, electrochemical equilibria, and equilibria at phase boundaries. Corequisite: Physics 7E or Engineering CBEMS40A or CBEMS45A; and Chemistry 5. Prerequisites: Chemistry 1C, Mathematics 2D, and Physics 7D.
130B Quantum Chemistry, Spectroscopy, and Bonding (4) W. Fundamentals of molecular quantum mechanics. Development of the principles of rotational, vibrational, electronic, and magnetic resonance spectroscopy. Chemical bonding. Applications to biological and condensed phase systems. Prerequisite: Chemistry 130A or Engineering CBEMS45C; Physics 7D or 7E.
130C Structure, Statistical Mechanics, and Chemical Dynamics (4) S. Kinetic theory and statistical mechanics with applications to gases, macromolecules, and condensed phases. Transport phenomena. Chemical kinetics. Prerequisite: Chemistry 130B.
131A-B-C Physical Chemistry: A Molecular Approach. Lecture, three hours; discussion, one hour.
131A Quantum Principles (4) F. Principles of quantum chemistry with applications to nuclear motions and the electronic structure of the hydrogen atom. Corequisite: Physics 7E, or Engineering CBEMS40A or CBEMS45C; and Chemistry 5. Prerequisites: Chemistry 1C, Mathematics 2D, and Physics 7D.
131B Molecular Structure and Elementary Statistical Mechanics (4) W. Principles of quantum mechanics with application to the elements of atomic structure and energy levels, diatomic molecular spectroscopy and structure determination, and chemical bonding in simple molecules. Prerequisites: Chemistry 131A; Physics 7E or Engineering CBEMS45C.
131C Thermodynamics and Chemical Dynamics (4) S. Energy, entropy, and the thermodynamic potentials. Chemical equilibrium. Chemical kinetics. Prerequisite: Chemistry 131B.
135 Methods of Molecular Structure Determination (4) F, W. Lecture, three hours; discussion, one hour. Determination of molecular structure using spectroscopic, diffraction, and scattering techniques. Prerequisites: Chemistry 130A-B-C or 131A-B-C.
137 Computational Chemistry (4) S. Lecture, three hours; discussion, one hour; laboratory, three hours. Short introduction to programming languages and to representative algorithms employed in chemical research. Students have the opportunity to devise and employ their own codes and also to employ codes which are widely used in various fields of chemistry. Corequisite: Chemistry 130B or 131B. Prerequisites: Chemistry 51A-B-C or H52A-B-C and 130A or 131A.
138 Introduction to Computational Organic Chemistry (4). Lecture, three hours; discussion, one hour; laboratory, three hours. An introduction to the use of computational chemistry to investigate reaction mechanisms, to calculate structures, and to predict properties of molecules. Students have the opportunity to perform calculations employing computational methods which are widely used in various fields of chemistry. Prerequisites: Chemistry 51A-B-C or H52A-B-C.
151 Quantitative Analytical Chemistry (4) F, Summer. Lecture, three hours; discussion, one hour. Theoretical aspects of methods in analytical chemistry. Topics include statistical treatment of data and the fundamental chemistry which underlies methods of chemical analysis. Corequisite: Chemistry 151L. Prerequisites: Chemistry 1A-B-C, 1LB-LC; 5; 51A-B-C and 51LA-LB-LC or H52A-B-C and H52LA-LB-LC.
151L Quantitative Analytical Chemistry Laboratory (2) F, Summer. Discussion, one hour; laboratory, six hours. Practical aspects of important methods in analytical chemistry. Laboratory analysis of standard samples. Laboratory experiments include methods of gravimetry, titrimetry, chromatography and other separation methods, spectrochemical and electrochemical measurements. The use of computer programs for the reduction of data from laboratory experiments is encouraged. Corequisite: Chemistry 151. Prerequisites: Chemistry 1A-B-C, 1LB-LC; 5; 51A-B-C and 51LA-LB-LC or H52A-B-C and H52LA-LB-LC.
152 Advanced Analytical Chemistry (5) W. Lecture, three hours; discussion, one hour; laboratory, seven hours. In-depth treatment of most modern instrumental methods for quantitative analysis of real samples and basic principles of instrument design. Laboratory experiments in the use of electronic test equipment, microprocessor programming; interfacing and use of techniques such as absorption, emission, and luminescence spectrophotometry, polarography, gas and liquid chromatography, magnetic resonance, neutron activation analysis, and mass spectrometry. Prerequisite: Chemistry 151 and 151L.
153 Physical Chemistry Laboratory (4) S. Prelaboratory lecture, three hours; laboratory, nine hours. Laboratory exercises emphasize quantitative characterization of chemical substances and chemical processes. Experiments in chemical thermodynamics, atomic and molecular spectroscopy, chemical kinetics, and various methods of molecular structure determination. Corequisite: Chemistry 130C or 131C. Prerequisites: Chemistry 151, 151L, and Chemistry 130A-B or 131A-B.
156 Advanced Laboratory in Chemistry and Synthesis of Materials (4) S. Lecture, two hours; laboratory, eight hours. Synthesis and characterization of organic and inorganic materials including polymers and oxides. Techniques include electron and scanning probe microscopy, gel permeation chromatography, x-ray diffraction, porosimetry, and thermal analysis. Prerequisite: Chemistry 130A-B or 131A-B or Engineering ENGR54. Same as Engineering CBEMS160.
160 Organic Synthesis Laboratory (4) W, S. Lecture, two hours; discussion, one hour; laboratory, eight hours. Modern experimental techniques in organic synthesis including experience with thin-layer chromatography, liquid chromatography, and gas chromatography. Modern methods of structure elucidation including FT NMR are employed in the characterization of products. Prerequisite: Chemistry 125.
170 Radioisotope Techniques (4) F, W. Lecture, three hours; laboratory, four to six hours. Basic theory and practice of production, separation, safe handling, counting, applications of radioactive isotopes with emphasis on applications in chemistry, biology, and medicine. Prerequisite: Chemistry 151, 151L.
177 Medicinal Chemistry (4) F, W. Lecture, three hours; discussion, one hour. An introduction of the basics of drug activity and mechanisms. Strategies used to identify lead compounds such as natural product chemistry, combinatorial chemistry, molecular modeling, and high-throughput screening. Relationship of molecular structure to pharmacological activity. Corequisite: Chemistry 177L. Prerequisites: Chemistry 51A-B-C or equivalent, and Biological Science 98 or Chemistry 128. Same as Pharmaceutical Sciences 177.
177L Medicinal Chemistry Laboratory (2) F, W. Laboratory, four hours. Laboratory accompanying Chemistry 177. Corequisite: Chemistry 177. Prerequisites: Chemistry 51A-B-C or equivalent, and Biological Science 98 or Chemistry 128. Same as Pharmaceutical Sciences 177L.
180 Undergraduate Research (4-4-4) F, W, S. The student wishing to engage in research for credit should arrange with a member of the faculty to sponsor and supervise such work. A student time commitment of 10 to 15 hours per week is expected, and a written research report is required at the end of each quarter of enrollment. Prerequisite: consent of a faculty sponsor.
H180A-B-C Honors Research in Chemistry (4-4-4) F, W, S. Undergraduate honors research in Chemistry. A student time commitment of 10-15 hours per week is required. Corequisite for H180C: Chemistry H181. Prerequisites: consent of instructor; open to participants in the Chemistry Honors program and to Chemistry majors participating in the Campuswide Honors Program.
H181 Honors Seminar in Chemistry (2) S. Students receive guidance in the preparation of oral and written research presentations. A written thesis is prepared and a formal research seminar is presented. Corequisite: Chemistry H180C. Prerequisites: successful completion of Chemistry H180A-B; satisfactory completion of the lower-division writing requirement. Open only to students in the Chemistry Honors Program and Chemistry majors who are participating in the Campuswide Honors Program.
191 Chemistry Outreach Program (2) F, W, S. Field work, six to eight hours; discussion, one hour. Involves intensive participation in the UCI Chemistry Outreach Program, which performs Chemistry demonstrations at local high schools. Pass/Not Pass only. May be taken for credit six times.
192 Tutoring in Chemistry (2) F, W, S. Enrollment limited to participants in the Chemistry Peer Tutoring Program. Prerequisite: consent of instructor. May be taken for a total of 18 units of which the first eight may be taken for a letter grade. The remaining 10 units must be taken Pass/Not Pass only. NOTE: No more than eight units may be counted toward the 180 units required for graduation. Satisfies no degree requirement other than contribution to the 180-unit total.
193 Research Methods (4) W, S. Lecture, three hours; laboratory, two hours. Explores tools of inquiry for developing and implementing science research projects. Students undertake independent projects requiring data collection, analysis, and modeling, and the organization and presentation of results. Additional topics include ethical issues and role of scientific literature. Prerequisite: Biological Sciences 14 or Physical Sciences 5. Same as Physics 193 and Biological Sciences 108.
199 Independent Study in Chemistry (1 to 4 per quarter). The student wishing to engage in independent study for credit should arrange with a member of the faculty to sponsor and supervise such work. A student time commitment of three to four hours per week per unit is expected, and a written report on the independent study is required at the end of each quarter of enrollment. Prerequisite: consent of instructor.
GRADUATE
201 Organic Reaction Mechanisms I (4). Lecture, three hours; discussion, one hour. Advanced treatment of basic mechanistic principles of modern organic chemistry. Topics include molecular orbital theory, orbital symmetry control of organic reactions, aromaticity, carbonium ion chemistry, free radical chemistry, the chemistry of carbenes and carbanions, photochemistry, electrophilic substitutions, aromatic chemistry. Prerequisite: Chemistry 130A-B-C or 131A-B-C or equivalent.
202 Organic Reaction Mechanisms II (4). Lecture, three hours; discussion, one hour. Topics include more in-depth treatment of mechanistic concepts, kinetics, conformational analysis, computational methods, stereoelectronics, and both solution and enzymatic catalysis. Prerequisite: Chemistry 201.
203 Organic Spectroscopy (4). Lecture, three hours; discussion, one hour. Modern methods used in structure determination of organic molecules. Topics include mass spectrometry; ultraviolet, chiroptical, infrared, and nuclear magnetic resonance spectroscopy. Prerequisite: Chemistry 51A-B-C or H52A-B-C.
204 Organic Synthesis I (4). Lecture, three hours; discussion, one hour. Fundamentals of modern synthetic organic chemistry will be developed. Major emphasis is on carbon-carbon bond forming methodology. Topics include carbonyl annelations, cycloadditions, sigmatropic rearrangements, and organometallic methods. Corequisite: concurrent enrollment in Chemistry 202.
205 Organic Synthesis II (4). Lecture, three hours; discussion, one hour. Fundamentals of modern synthetic organic chemistry will be developed. Major emphasis this quarter is on natural product total synthesis and retrosynthetic (antithetic) analysis. Prerequisite: Chemistry 204.
206 Laboratory Skills (4 to 6). Lecture, three hours; laboratory, six to ten hours. Introduces students to a variety of practical laboratory techniques, including lock-in, boxcar, coincidence counting, noise filtering, PID control, properties of common transducers, computer interfacing to instruments, vacuum technology, laboratory safety, basic mechanical design, and shop skills. Prerequisite: consent of instructor. Same as Physics 206. Concurrent with Physics 106.
207 Chemistry for Physicists (4). Lecture, three hours; discussion, one hour. Introduction to fundamental concepts in molecular structure and reactivity: theory of bonding, valence and molecular orbitals; structure and reactivity in inorganic chemistry; elements in molecular group theory; nomenclature in organic chemistry; and survey of macromolecules. Same as Physics 207.
208 Mathematics for Chemists (4). Lecture, three hours; discussion, one hour. Applications of mathematics to physical and chemical problems. Calculus of special functions, complex variables and vectors; linear vector spaces and eigenvalue problems. Differential equations. Same as Physics 208.
209 Physics for Chemists (4). Lecture, three hours; discussion, one hour. An introduction to concepts of electrodynamics with special emphasis on applications to chemistry: vector analysis, electrostatics, magnetostatics, electrodynamics, electromagnetic waves, classical radiation theory, special relativity.
213 Chemical Kinetics (4) S. Lecture, three hours; discussion, one hour. Surveys gas phase and organic reaction mechanisms and their relationship to kinetic rate laws; treats the basic theory of elementary reaction rates. A brief presentation of modern cross-sectional kinetics is included. Prerequisites: Chemistry 130A-B-C or 131A-B-C or equivalent.
215 Inorganic Chemistry I (4). Lecture, three hours; discussion, one hour. Principles of modern inorganic chemistry with applications to chemical systems of current interest. Inorganic phenomena are organized into general patterns which rationalize observed structures, stabilities, and physical properties. Prerequisites: Chemistry 107 and 130A-B-C or 131A-B-C or equivalent.
216 Organometallic Chemistry (4). Lecture, three hours; discussion, one hour. Synthesis and reactivity of organometallic complexes with an emphasis on mechanisms. Topics include bonding and fluxional properties; metal-carbon single and multiple bonds; metal š-complexes. Applications to homogenous catalysis and organic synthesis are incorporated throughout the course. Prerequisite: Chemistry 107 or 215.
217 Physical Inorganic Chemistry (4). Lecture, three hours; discussion, one hour. General principles of the spectroscopy and magnetism of inorganic compounds. Characterization of inorganic complexes by infrared, near-infrared, visible, ultraviolet, NMR, EPR, EXAFS, and Mossbauer spectroscopies. Some necessary group theory developed. Prerequisite: Chemistry 215 or consent of instructor.
218 Metallobiochemistry (4). Lecture, three hours; discussion, one hour. A review of the biochemistry of metallic elements emphasizing: methods for studying metals in biological systems; the chemical basis for nature's exploitation of specific elements; structures of active sites; mechanisms; solid-state structures and devices; metals in medicine. Prerequisite: Chemistry 130A-B-C or equivalent.
219 Chemical Biology (4). Lecture, three hours; discussion, one hour. A survey of the organic chemistry underlying biological function. Introduction to chemical genetics, receptor-ligand interactions, small molecule agonists and antagonists, combinatorial synthesis, high throughput assays, molecular evolution, protein and small molecule design. Prerequisite: graduate standing or consent of instructor.
220 Bioorganic Chemistry (4). Lecture, three hours; discussion, one hour. Structure and function of biologically important macromolecules. Introduction to nucleic acids, protein structure, principles of molecular recognition, enzyme function, modeling, and engineering. Prerequisite: Chemistry 51A-B-C or H52A-B-C or equivalent.
221A Fundamentals of Molecular Biophysics (4) S. An overview of the principles and concepts in molecular biophysics. Topics covered include energy and entropy in biology, non-equilibrium reaction kinetics, random walks and molecular diffusion, molecular forces in biology. Prerequisites: undergraduate courses in physical chemistry and biochemistry, or consent of instructor.
221B Molecular Biophysics (4) F. A study of the biophysics of macromolecules and cells from a molecular perspective. Topics covered include protein folding, single molecule reaction kinetics, nucleic acid translation and transcription, molecular motors, cellular signal transduction. Prerequisites: Chemistry 221A and undergraduate courses in physical chemistry and biochemistry, or consent of instructor.
222 Natural Products (4) F. Lecture, three hours; discussion, one hour. Fundamentals of natural products chemistry are surveyed. Topics include classification schemes, biosynthesis, isolation and characterization, drug development from natural products, and chemical synthesis.
225 Polymer Chemistry: Synthesis and Characterization of Polymers (4). Lecture, three hours; discussion, one hour. Structure of synthetic and natural polymers. Survey of modern polymer synthetic methods. Molecular weight and molecular weight distribution. Chain conformation and stereochemistry. Introduction to polymer characterization, chain models, and solution behavior. Prerequisite: undergraduate courses in organic and physical chemistry; or consent of instructor.
226 Polymer Materials: Polymer Structure-Property Relationships (4). Lecture, three hours; discussion, one hour. Chain length and copolymer sequence distributions. Polymer chain models and configurational statistics. Melting and glass transitions in crystalline and amorphous polymers. Network theory. Elasticity and viscoelasticity. Solution theory and phase equilibria. Mechanical and materials properties. Prerequisite: undergraduate courses in organic and physical chemistry; or consent of instructor.
227 Molecular Modeling (4). Laboratory, four hours. Concepts of molecular mechanics and electronic structure theory, and applications to practical chemical questions. Topics include prediction of conformational preference, reactivity, and selectivity. A hands-on course with numerous worked problems and examples using graphics workstations. Prerequisite: consent of instructor.
228 Electromagnetism (4). Lecture, three hours; discussion, one hour. Maxwell's equations, electrodynamics, electromagnetic waves and radiation, wave propagation in media, interference and quantum optics, coherent and incoherent radiation, with practical applications in interferometry, lasers, waveguides, and optical instrumentation. Prerequisite: consent of instructor. Same as Physics 228.
229A-B Computational Methods (4-4). Lecture, three hours; laboratory, six hours. Mathematical and numerical analysis using Mathematica and C programming, as applied to problems in physical science. Prerequisite: consent of instructor. Same as Physics 229A-B.
230 Classical Mechanics and Electromagnetic Theory (4). Lecture, three hours; discussion, one hour. The fundamentals of classical mechanics and electromagnetic theory are developed with specific application to molecular systems. Newtonian, Lagrangian, and Hamiltonian mechanics are developed. Boundary value problems in electrostatics are investigated. Multipole expansion and macroscopic media are discussed from a molecular viewpoint. Prerequisite: Chemistry 131A-B-C or equivalent.
231A-B-C Quantum Mechanics and Spectroscopy. Lecture, three hours; discussion, one hour.
231A Fundamentals of Quantum Mechanics (4) F. The postulates of quantum mechanics are discussed and applied to a variety of model problems. Prerequisites: Chemistry 131A-B-C or equivalent.
231B Applications of Quantum Mechanics (4) W. Approximate methods for solving atomic and molecular structure problems are developed, and the application of quantum mechanics to spectroscopy is introduced. Prerequisite: Chemistry 231A or consent of instructor.
231C Molecular Spectroscopy (4) S. Theory and techniques of spectroscopy as used for the study of molecular and condensed phase properties. Coherent time domain spectroscopies are covered. Prerequisite: Chemistry 231B or consent of instructor.
232A Thermodynamics and Introduction to Statistical Mechanics (4) W. Lecture, three hours; discussion, one hour. A detailed discussion from an advanced point of view of the principles of classical thermodynamics. The fundamentals of statistical mechanics. Topics include an introduction to ensemble theory, Boltzmann statistics, classical statistical mechanics, and the statistical mechanics of ideal gas systems. Prerequisite: Chemistry 130A-B-C or 131A-B-C or equivalent.
232B Advanced Topics in Statistical Mechanics (4) S. Continued discussion of the principles of statistical mechanics. Applications to topics of chemical interest including imperfect gases, liquids, solutions, and crystals. Modern techniques such as the use of autocorrelation function methods. Prerequisite: Chemistry 232A or equivalent.
232C Non-Equilibrium Statistical Mechanics (4) F. Lecture, three hours; discussion, one hour. Phenomenology of material processes, including: kinetic theories of transport and continuum, linear response theory, critical phenomena of phase transition, self-assembly, and nucleation. Prerequisite: consent of instructor.
233 Nuclear and Radiochemistry (4). Lecture, three hours. Advanced treatment (beyond that in Chemistry 170) of nuclear structure, nuclear reactions, and radioactive-decay processes. Introduction to nuclear activation analysis, isotope effects, radiation chemistry, hot-atom chemistry, nuclear age-dating methods, nuclear reactors, and nuclear power. Prerequisite: Chemistry 170 or equivalent or consent of the instructor.
234 Advanced Chemical Kinetics (4). Topics and format vary. Prerequisite: Chemistry 213 or consent of the instructor.
235 Molecular Quantum Mechanics (4) W. Lecture, three hours; discussion, one hour. Application of quantum mechanics to calculation of molecular properties. Electronic structure of molecules. Prerequisite: Chemistry 231A or equivalent.
236 Forces Between Molecules (4) F. Lecture, three hours; discussion, one hour. The nature and effects of non-covalent interactions between molecular systems. The focus is on properties of these interactions in condensed phases: macromolecular systems; particle-surface interactions.
241 Current Issues Related to Tropospheric and Stratospheric Processes (4) S. Lecture, three hours. Examination of current issues related to the atmosphere, including energy usage; toxicology; effects on humans, forest, plants, and ecosystems; particulate matter (PM10); combustion; modeling and meteorology; airborne toxic chemicals and risk assessment; application of science to development of public policies. Prerequisite: One course selected from Chemistry 245, Earth System Science 202, Engineering MAE164, Engineering MAE261, or consent of instructor. Same as Engineering MAE 260.
242A Physical and Geometrical Optics (4) W. Lecture, three hours; discussion, one hour. Focuses on the practical aspects of optics and optical engineering, starting at the fundamentals. Topics include geometrical optics, ray tracing, polarization optics, interferometers, and diffractive optics. Prerequisite: consent of instructor.
242B Applied Optics (4) S. Lecture, three hours; discussion, one hour. Focuses on the treatment of a wide variety of tools and techniques used in optics, in particular in research. Subjects include an introduction to lasers, optical detection, coherent optics, spectroscopic techniques, and selected topics corresponding to the interest of the students. Prerequisite: Chemistry 242A or consent of instructor. Formerly Chemistry 242.
243 Advanced Instrumental Analysis (4) W. Lecture, three hours. Theory and applications of modern advanced instrumental methods of analysis. Includes data acquisition, storage, retrieval and analysis; Fourier transform methods; vacuum technologies, magnetic sector, quadrupole, and ion trap mass spectrometry; surface science spectroscopic methods; lasers and optics. Prerequisites: Chemistry 152 and Chemistry 130A-B-C or 131A-B-C.
245 Atmospheric Chemistry of the Natural and Polluted Troposphere (4) F. Lecture, three hours; discussion, one hour. Kinetics, mechanisms, and photochemistry of tropospheric reactions in the gas, liquid, and solid phases, and methods of analysis. Chemistry of photochemical oxidant formation and acid deposition, and applications to control strategies. Chemistry of toxic chemicals and indoor air pollution. Prerequisites: Chemistry 130A-B-C or 131A-B-C and Chemistry 151 and 151L or equivalent.
246 Separations and Chromatography (4). Lecture, three hours; discussion, one hour. Introduction to modern separation techniques such as gas chromatography, high-performance liquid chromatography, supercritical fluid chromatography, capillary electrophoresis, and field flow fractionation. Applications of these separation strategies are discussed.
247 Current Problems in Analytical Chemistry (4). Lecture, three hours; discussion, one hour. Surveys current research challenges in analytical chemistry. Topics include electrochemistry, chromatography, spectroscopy, and mass spectrometry.
248 Electrochemistry (4). Lecture, three hours; discussion, one hour. Fundamentals of electrochemistry including thermodynamics and the electrochemical potential, charge transfer kinetics, and mass transfer. Methods based on controlled potential and controlled current are described; the effects of slow heterogeneous kinetics and the perturbation caused by homogeneous chemistry are discussed.
249 Analytical Spectroscopy (4). Lecture, three hours; discussion, one hour. Advanced treatment of spectroscopic techniques and instrumentation. Atomic and molecular absorption, emission, and scattering processes and their application to quantitative chemical analysis are outlined. Puts different spectroscopic techniques in perspective and demonstrates most appropriate applications to analytical problems.
251 Special Topics in Organic Chemistry (1 to 4). Advanced topics in organic chemistry. Prerequisite: consent of the instructor.
252 Special Topics in Physical Chemistry (1 to 4). Advanced topics in physical chemistry. Prerequisite: consent of the instructor.
253 Special Topics in Inorganic Chemistry (1 to 4). Advanced topics in inorganic chemistry. Prerequisite: Chemistry 215 or consent of the instructor.
266 Current Topics in Chemical and Materials Physics (1). Lecture, one hour; discussion, one hour. The subjects covered vary from year to year. Connection between fundamental principles and implementations in practice in science, industry, and technology. Prerequisite: consent of instructor. Same as Physics 266.
271 Structural X-ray Crystallography (4). Lecture, three hours; discussion, one hour. The principles and practice of the determination of structures by single crystal x-ray diffraction techniques. Crystal symmetry, diffraction, structure solution and refinement. Opportunities for hands-on experience in structure determination. Prerequisite: Chemistry 130A-B-C or Chemistry 131A-B-C or equivalent.
272 Industrial Chemistry (4). Lecture, three hours; discussion, one hour. Scientific, economic, and environmental aspects of the top 50 industrially produced chemicals, including how they are obtained and used, present and future sources of energy and raw materials, and the effects of chemical manufacturing on the price structure of our economy. Prerequisite: consent of instructor.
273 Technical Communication Skills (2). Lecture, one hour; discussion, three hours. Development of effective communication skills, oral and written presentations, through examples and practice. Prerequisite: consent of instructor. Satisfactory/Unsatisfactory only. Same as Physics 273.
280 Research (2 to 12) F, W, S. Supervised original research toward the preparation of a Ph.D. dissertation or M.S. thesis. Prerequisite: consent of the instructor.
290 Seminar (1) F, W, S. Weekly seminars and discussions on general and varied topics of current interest in chemistry. Prerequisite: graduate standing. May be repeated for credit.
291 Research Seminar (4). Detailed discussion of research problems of current interest in the Department. Format, content, and frequency of the course are variable. Prerequisite: consent of instructor.
292 Graduate Symposium (2) F. Students present public seminars on literature-based research topics in contemporary chemistry. Topics to be chosen by student and approved by instructor. May be repeated for credit as topics vary.
299 Independent Study (1 to 4) F, W, S. Prerequisite: consent of instructor.
399 University Teaching (1 to 4) F, W, S. Required of and limited to Teaching Assistants.