Undergraduate Courses in Biological Sciences
(Schedule of Classes designation: Bio Sci)

Core Curriculum / Upper-Division Laboratories / Upper-Division Electives /

1A Life Sciences (4) F, W, S. Lecture, three hours. Designed to introduce nonmajors to the basic concepts of modern biology. Discussion of evolutionary biology, ecology, molecular biology, and genetics. Open to nonmajors only. (II)

2A Freshman Seminars (2) F. Seminar, 1.5 hours. Weekly meetings consisting of presentations by faculty, professional staff, and Peer Academic Advisors provide information about the School of Biological Sciences, campus resources, learning skills, and special programs/opportunities. Pass/Not Pass only. Open to freshman Biological Sciences majors only.

3A Career Decision Making (0). Lecture, one hour. An introductory course designed to facilitate the career decision-making process. Decision-making processes, values, and standardized tests of aptitudes, interests, and values are utilized with non-test data in appraising biological sciences career options. Pass/Not Pass only. One unit of workload credit only.

3B Non-Health Sciences Career Exploration (0). Lecture, one hour. A survey course designed to assist students in exploring non-health science career options. Lectures by professionals in various fields. Pass/Not Pass only. One unit of workload credit only.

5 Introduction to Molecular Biology (4). Lecture, three hours. Molecules of life, with emphasis on medical applications. Open to nonmajors only. No credit given for Biological Sciences 5 if taken after Biological Sciences 99. (II)

6 Tropical Biology: Race to Save the Tropics (4). Lecture, three hours. Population growth combines with tropical resource consumption by industrialized nations to cause high rates of deforestation, pollution, habitat fragmentation, and extinction of species. Discusses tropical biomes, their population, community, and ecosystem processes, and possible means of conservation of biodiversity. (II)

9A Nutrition Science (4) F, W. Lecture, three hours. An introduction to nutrition science, integrating concepts from biology, biochemistry, microbiology, physiology, and psychology to explain the interaction between nutrients and the human body. Biological basis of nutrient standards is analyzed. Effects of nutrition, behavior, exercises on health/disease. (II)

9B Biology and Chemistry of Food and Cooking (4) S. Lecture, three hours. The kitchen is used as a laboratory to introduce fundamental principles of biology, chemistry, and physics. A molecular/cellular analysis of cooking, including concepts such as protein structure, browning reactions, colloids, emulsions, carbohydrate metabolism, and development of flavor/texture through biochemical transformations. (II)

9C Biotech Basics (4). Lecture, three hours. An overview of current biotechnology. Discusses the biological/molecular basis of novel therapies for diseases, modification of human genes, human genome project, cloning, DNA fingerprinting, and genetically modified food. Targeted for students interested in modern breakthroughs in biology. (II)

9D Diseases of the Twenty-First Century (4) F. Lecture, three hours. Why do we get sick? An introduction to the biological basis of human disease, including diseases of the cardiovascular, respiratory, nervous, and reproductive systems. Case studies present diagnosis, treatment, and prevention protocols. Inheritable and infectious diseases also discussed. Only one course from Biological Sciences 9D, 10, and 12D may be taken for credit. (II)

9E Horticulture Science (4). Lecture, two hours; laboratory, two hours; field work, one weekend day per quarter. Scientific principles of horticulture at the UCI Arboretum. Taxonomy, plant life history strategies; experiments with seed dormancy; morphological adaptations for specialized sexual and clonal reproduction; basics of plant propagation and ecological restoration. Laboratory fee. (II)

9G Way Your Body Works (4). Lecture, three hours. An introduction to the basic mechanisms that control the organ systems of the human body, including the nervous, cardiovascular, immune, and reproductive systems. Emphasis is on how the body works normally, but includes how these processes fail in disease. Open to nonmajors only. (II)

9J Biology of Oriental Medicine (4) W. Lecture, three hours. With lectures, demonstrations, and hands-on learning, the theory and practice of herbal medicine, acupuncture, qigong, and manipulative therapies are explained in Western biomedical terms. The latest basic and clinical research advances in each area are also described. Only one course from Biological Sciences 9J, 9N, and D124 may be taken for credit. (II)

9K Global-Change Biology (4) W. Lecture, three hours; discussion, one hour. Addresses ways in which humans are altering the global environment, with consequences for the ecology of animals, plants, and microbes. Discussion on how these biologically oriented questions relate to human society, politics, and the economy. Same as Earth System Science 13. (II)

9N Introduction to Complementary and Alternative Medicine (4) Summer. Lecture, three hours. Basic and clinical research on complementary and alternative therapies (e.g., herbal medicine, mind-body practices, energy medicine, acupuncture, homeopathy, chiropractic, Ayurveda), and how such practices are integrated into Western medicine are discussed. Includes lectures, demonstrations, and hands-on learning. Open to nonmajors only. Biological Sciences 9N and 10 may not both be taken for credit. Only one course from Biological Sciences 9N, 9J, and D124 may be taken for credit. (II)

10 The Biology of Human Diseases (4). Lecture, three hours. Introduction to concepts of diagnosis, treatment, and prevention of major human infectious diseases. Covers some aspects of epidemiology. Scope and impact of infectious diseases in the present and past experiences in controlling infectious disease. Reviews the biology of human organ systems. Only one course from Biological Sciences 9D, 10, and 12D may be taken for credit. (II)

11 Topics in Biological Sciences (4) F, W, S. Lecture, three hours. Studies in selected areas of biological sciences. May be taken for credit three times as topics vary. (II)

12B Disease and Civilization (4). Lecture, three hours. To demonstrate the role played by infectious diseases on the development of human civilization. The psychological impact of major epidemic diseases upon society and culture. Starting with early hunting and gathering cultures through the effect of AIDS in the modern world. (II)

12D Molecular Basis of Human Disease (4). Lecture, four hours. Introduction to the concepts of the molecular basis, treatment, and diagnosis of human disease. Diseases resulting from infectious agents such as virus, bacteria, protozoan and metazoan animals, and diseases resulting from genetic disorders discussed in context of molecular mechanisms. Only one course from Biological Sciences 9D, 10, and 12D may be taken for credit. (II)

14 California Teach 1: Introduction to Science and Mathematics Teaching (3) F, W, S. Seminar, three hours. First in a series for students interested in becoming middle or high school teachers of mathematics or science. Students gain an understanding of effective, research-based teaching strategies. Includes supervised field experience in a K-12 classroom. Same as Physical Sciences 5.

16 Introduction to Darwinian Biology (4) W. Lecture, three hours. An introduction to the basic concepts of ecology, evolution, and functional biology suitable for non-scientists. Open to nonmajors only. (II)

20 California Natural History (4) F. Lecture, three hours. Introduction to ecological relationships within a variety of California habitats. Explores aspects of the physical environments and the adaptations of organisms to their physical and biological surroundings in habitats such as the coastal zone, mountains, and deserts. (II)

25 Biology of Cancer (4) W. Lecture, four hours. Biological, clinical, and psychosocial nature of cancer through the perspectives of medical researchers, biologists, physicians, and health educators. For students of all majors, designed so that each can increase personal awareness of the biology of cancer. No credit for Biological Sciences 25 if taken after Biological Sciences M125. (II)

30 Biomedical Ethics (4) S. Lecture, three hours. Ethical issues inherent in twenty-first-century biological and medical advances. An introduction to the basic biology underlying these issues and an analysis of the ethical implications to society. Topics such as cloning, stem cell research, genetic engineering are discussed by guest speakers.

32 Evidence-Based Medicine (4) Summer. Lecture, three hours. Basic concepts of biomedical research, clinical traits, and evaluation of data. Case studies of Western drugs and alternative therapies, including acupuncture, herbal medicine, and mind and body practices. Relevance to socioeconomics and political issues associated with America's healthcare system. (II)

35 The Brain and Behavior (4). Lecture, three hours. Introduction to how the brain works. Biological processes underlying perception, movement, sleep-wake cycles, motivation, language, learning, and memory. Changes in the brain associated with sex differences, drug use, aging, seasons, and time of day. Fundamental properties of the nervous system. Open to nonmajors only. (II)

36 Drugs and the Brain (4). Lecture, three hours. Introduction to the actions of drugs on the brain. How studying drug action helps to reveal normal functions of neurons. How drugs can correct neural disorders or disrupt neural function. Biological issues related to drug abuse, drug addiction, and drug seeking. Open to nonmajors only. (II)

37 Brain Dysfunction and Repair (4). Lecture, three hours. Introduction to the disruptions in brain function that underlie disorders such as Alzheimer's disease, Parkinsonism, schizophrenia, and depression, and the basis for drug therapies. The brain's ability to repair itself after damage and the pros and cons of that repair. Open to nonmajors only. (II)

38 Mind, Memory, Amnesia, and the Brain (4) S. Lecture, three hours. Introduction to neural mechanisms underlying learning and memory. Emphasis on molecular changes that mediate memory as well as structures involved in different forms of memory. Additionally, the biology of memory phenomena, from extraordinary memory to false memory to amnesia is examined. Open to nonmajors only. (II)

42 Origin of Life (4) W. Lecture, three hours. Biochemical explanations for the origin of life are presented. Topics include definitions of life, the first replicating molecules, the first catalyzed biosynthesis and metabolism, the origin of cells (compartmentalization) and the origins of information and the genetic code. (II)

45 AIDS Fundamentals (4) F, W. Lecture, three hours; discussion, one hour. Considers the biological and sociological bases of the AIDS epidemic. Topics include the history of AIDS, current medical knowledge, transmission, risk reduction, and how the community can respond. Same as Public Health 80. (II)

46 Discussion and Literature Research in AIDS (2 to 4) F, W. Discussion, two hours; research, two hours. Students carry out two activities: (1) leading discussions about HIV/AIDS (predominantly regarding sociological and personal reactions) among students taking the AIDS Fundamentals course and (2) literature research about biomedical aspects of AIDS. Prerequisite: Biological Sciences 45 or Planning, Policy, and Design 45 or Public Health 80; consent of instructor.

55 Introduction to Ecology (4). Lecture, three hours. Principles of ecology; application to populations, communities, ecosystems, and humans. Open to nonmajors only. No credit given for Biological Sciences 55 if taken after Biological Sciences 96 or E106. (II)

65 Biodiversity and Conservation (4) W. Lecture, three hours. A biological perspective on the current environmental crisis. The origin, evolution, and value of biological diversity. Extinction and depletion caused by overexploitation, habitat loss, and pollution. Conservation through habitat preservation and restoration, captive breeding, cryopreservation. (II)

75 Human Development: Conception to Birth (4) W, S. Lecture, three hours. Processes leading to the birth of a healthy child and the avoidance of birth defects. Male and female reproductive systems, hormonal control of egg-sperm formations, sexual intercourse, contraception, venereal diseases, fertilization, cell division, embryonic development, fetal physiology. Open to nonmajors only. (II)

H90 The Idiom and Practice of Science (4). The importance of biological sciences in our world are discussed. Topics may include brain and behavior, health and disease, genetics and society, and conservation biology. A primary goal is to encourage students to understand better the world in which they live. Prerequisite: restricted to members of the Campuswide Honors Program. (II)

92 Special Group Activities

Sec. 3 Reading, Writing, and Reasoning for Health Science (4) F, W, S. Designed to strengthen biology students' reading, writing, and critical thinking skills to ensure their success at the University and to prepare them for graduate study in medicine, dentistry, optometry, or public health. Pass/Not Pass only. Open to Biological Sciences majors only.

Sec. 5 Curriculum (2). Initiation, planning, and coordination of student-run courses. Prerequisite: consent of instructor. Pass/Not Pass only. May be taken for credit for a total of 12 units.

101 California Teach 2: Middle School Science and Mathematics Teaching (3) F, W. Seminar, three hours. Second in a series for students interested in becoming middle or high school teachers of mathematics or science. Students gain an understanding of effective, research-based teaching strategies for grades 6-8. Includes supervised field experience in a middle school classroom. Prerequisite: Biological Sciences 14. Same as Physical Sciences 105.

102 California Teach 3: High School Science and Mathematics Teaching (2) F, W. Seminar, 1.5 hours; field work, 1.5 hours. Capstone of a series of three seminars for students interested in becoming secondary mathematics or science teachers. Meets six times for students to understand effective, research-based teaching strategies. Includes an opportunity to experience teaching in a high school. Prerequisites: Biological Sciences 14 and 101. Same as Physical Sciences 106.

108 Research Methods (4) W. Lecture, three hours; laboratory, two hours. Explores tools of inquiry for developing and implementing science research projects. Students undertake independent projects requiring data collection, analysis, and modeling, and the organization and presentation of results. Additional topics include ethical issues and role of scientific literature. Prerequisite: Biological Sciences 14 or Physical Sciences 5. Same as Chemistry 193 and Physics 193.

190 Transfer Student Seminars (1). Lecture, one hour; seminar, one hour. Weekly meetings consisting of presentations by faculty, professional staff, and New Student Peer Academic Advisors provide information about the School of Biological Sciences, campus resources, and special programs/opportunities. Pass/Not Pass only. Open to new transfer students only.

CORE CURRICULUM

Prerequisites listed for Core courses are rigorously enforced. (Transfer students who have successfully completed one or more years of college biology should consult with the Biological Sciences Student Affairs Office for possible exemption from portions of the Core.)

93 From DNA to Organisms (4) F. Lecture, three hours; discussion, one hour. Course may be offered online. Cell biology, biochemistry, genetics, and the biology of organ systems. Covers concepts of building blocks (nucleotides, amino acids, and cells) and of information flow (DNA to proteins, receptors to nuclei, the blood to distant organs, and DNA to offspring). No credit given for Biological Sciences 93 if taken after Biological Sciences 97 and/or 98. (II)

94 From Organisms to Ecosystems (4) W. Lecture, three hours; discussion, one hour. Patterns of diversity, ecology, and evolutionary biology. Emphasis is on the Tree of Life and how its members are distributed and interact. Prerequisite: Biological Sciences 93 with a grade of C- or better. No credit given for Biological Sciences 1A if taken after Biological Sciences 94. (II)

97 Genetics (4) F. Lecture, three hours; discussion, one hour. Introduction to genetics. Basic features of the replication and expression of DNA; cell division; and gene transmission. Recombination and mutation in diploid organisms. Prerequisite: Biological Sciences 94 with a grade of C- or better.

98 Biochemistry (4) W. Lecture, three hours. Structure and properties of proteins; major biochemical pathways and mechanisms for their control. Prerequisites: Biological Sciences 97 with a grade of C- or better and completion of or concurrent enrollment in Chemistry 51B or 52B.

99 Molecular Biology (4) S. Lecture, three hours. Biochemistry and replication of nucleic acids; molecular genetics; protein biosynthesis; genetic code; regulation of expression of genetic information; biochemical evolution. Prerequisite: Biological Sciences 98 with a grade of C- or better.

100 Scientific Writing (3) F, W, S, Summer. Lecture, two hours. Designed to give an overview of the basic aspects of scientific writing relevant to reporting research in the Biological Sciences. Corequisite or prerequisite: Biological Sciences 194S. Prerequisites: Biological Sciences 99; satisfactory completion of the lower-division writing requirement. Pass/Not Pass only.

D103 Cell Biology (4) F, W. Lecture, three hours; discussion, one hour. Analysis of the basic structure and function of animal cells, with an emphasis on the regulation of cellular processes. The basic features of membranes, cellular compartmentalization, protein trafficking, vesicular transport, cytoskeleton, adhesion, signal transduction, and cell cycle are covered. Prerequisite: Biological Sciences 99. Biological Sciences D103 and 107 may not both be taken for credit.

D104 Developmental Biology (4) W. Lecture, three hours; discussion, one hour. Cellular and molecular analysis of how a fertilized egg develops into an organism consisting of complex structures such as the eye, arms, and brain. Emphasis is on the key concepts of developmental processes underlying pattern formation, growth, and regeneration. Corequisite or prerequisite: Biological Sciences D103. Biological Sciences D104 and 108 may not both be taken for credit.

D105 Cell, Developmental, and Molecular Biology of Plants (4) F. Lecture, three hours. Emphasizes the special features of plant cells and plant development as compared to animals. Plants' ability to fuel our planet through photosynthesis and the interactions of plants with microorganisms in making nitrogen available to other life forms are two central topics. Prerequisite: Biological Sciences 99.

E106 Processes in Ecology and Evolution (4) S. Lecture, three hours; discussion, one hour. An in-depth study of the mechanisms that drive evolution and ecology including: natural selection, mutation, genetic drift, speciation, extinction, life history patterns, population dynamics, ecosystem and community structure, predator-prey and host pathogen interactions, and social behavior. Prerequisite: Biological Sciences 94. May be used as a course repeat of Biological Sciences 96. Biological Sciences E106 and 96 may not both be taken for credit.

E109 Human Physiology (4) F. Lecture, three hours. Functional features of the major organ systems in the human body. Emphasis on homeostasis and the interactions of organ systems in health and disease. (Discussion of behavior and brain function deferred to Biological Sciences N110.) Prerequisite: Biological Sciences 99. Biological Sciences E109 and Pharmaceutical Sciences 120 may not both be taken for credit.

N110 Neurobiology and Behavior (4) S. Lecture, three hours. Consideration of the evolution of behavior, including ethological and psychological aspects and analysis of neuroanatomical, neurochemical, neurophysiological, and neuroendocrine systems underlying basic behavioral processes. Corequisite or prerequisite: Biological Sciences 99.

UPPER-DIVISION LABORATORIES

D111L Developmental and Cell Biology Laboratory (4) F, W, S. Laboratory, three hours; lecture, two hours. Students study the division of cells, isolate cellular organelles (chloroplasts, mitochondria, nuclei), and follow changes in cells undergoing programmed cell death. Development is demonstrated in experiments showing cooperation of individual cells in forming a multicellular organism. Corequisites or prerequisites: Biological Sciences 100 and either Biological Sciences D103, D104, or D105. Prerequisite: Biological Sciences 194S. At the First Open Enrollment, this lab will be restricted to students who require it for completion of their degree. This enrollment restriction will be lifted at the beginning of the Second Open Enrollment Period.

E106L Habitats and Organisms (4) F. Field work, three hours; lecture, one hour. Introduces students to local habitats and organisms through required field trips and applies ecological and evolutionary principles from Biological Sciences E106. Students also explore related literature. Corequisites or prerequisites: Biological Sciences 100 and E106. Prerequisite: Biological Sciences 194S. Biological Sciences E106L may not be taken concurrently with or after taking Biological Sciences E166L. At the First Open Enrollment, this lab will be restricted to students who require it for completion of their degree. This enrollment restriction will be lifted at the beginning of the Second Open Enrollment Period.

E112L Physiology Laboratory (3) F, W, S. Laboratory, four hours. Corequisite or prerequisite: Biological Sciences 100. Prerequisites: Biological Sciences 194S and either Biological Sciences E109 or Engineering BME120 and BME121. Biological Sciences E112L and Pharmaceutical Sciences 120L may not both be taken for credit. At the First Open Enrollment, this lab will be restricted to students who require it for completion of their degree. This enrollment restriction will be lifted at the beginning of the Second Open Enrollment Period.

E115L Evolution Laboratory (4) S. Laboratory, four hours. Students perform experiments which illustrate important concepts in evolutionary biology such as natural selection, random genetic drift, inbreeding, age-specific selection, sexual selection, and phylogenetic reconstruction. Corequisites or prerequisites: Biological Sciences 100 and either Chemistry 51B or 52B. Prerequisites: Biological Sciences 97 with a grade of C- or better and Biological Sciences 194S. At the First Open Enrollment, this lab will be restricted to students who require it for completion of their degree. This enrollment restriction will be lifted at the beginning of the Second Open Enrollment Period.

E131L Image Analysis in Biological Research (4) S. Laboratory, three hours. Introduction to scientific image analysis including techniques such as high-speed, time-lapse, thermal imaging, and flow visualization. Students will make movies using cameras, edit and analyze images using computers, and do a writing project. Corequisite or prerequisite: Biological Sciences 100. Prerequisites: Biological Sciences E106 or E109, and 194S.

E161L Biology of Birds Lab (4). Laboratory, three hours. The companion to Biology of Birds (E160). This course consists primarily of field trips to identify local birds and study avian natural history. Students must provide their own transportation to field sites, some with entrance fees. Students must have field binoculars. Corequisite: Biological Sciences E160. Corequisites or prerequisites: Biological Sciences 94 and 100. At the First Open Enrollment, this lab will be restricted to students who require it for completion of their degree. This enrollment restriction will be lifted at the beginning of the Second Open Enrollment Period.

E166 Field Methods in Ecology (6) F. Laboratory, eight hours. Field studies of major concepts in plant and animal ecology, with emphasis on experimental design, field sampling methods, statistical analysis, and scientific writing. An independent project and two field trips are required. Corequisite or prerequisite: Biological Sciences 100. Prerequisites: Biological Sciences 194S and E106; satisfactory completion of the lower-division writing requirement.

E172L Plant Systematics Laboratory (4) S. Laboratory, two hours; Field work, one hour. Diversity of flowering plants is investigated in the laboratory and field. Familiarity with flowering plant families, particularly those prominent in the California flora, is emphasized. Corequisites or prerequisites: Biological Sciences 100 and E172. Prerequisites: Biological Sciences E106 and 194S. Concurrent with Ecology and Evolutionary Biology 273. At the First Open Enrollment, this lab will be restricted to students who require it for completion of their degree. This enrollment restriction will be lifted at the beginning of the Second Open Enrollment Period.

E179L Field Freshwater Ecology (4) S. Field work, three hours. Analytical techniques for common water-quality variables of lakes, streams, rivers. Benthic fauna, vertebrates, and invertebrates, algae, and aquatic plants. Emphasis on field methods with an experimental approach; laboratory exercises. Field trips to marshes, lakes, vernal pools, rivers, and streams. Corequisites or prerequisites: Biological Sciences 100 and E179. At the First Open Enrollment, this lab will be restricted to students who require it for completion of their degree. This enrollment restriction will be lifted at the beginning of the Second Open Enrollment Period.

M114L Biochemistry Laboratory (4) F, W, S. Laboratory, four hours; lecture, two hours. Properties of enzymes and the culture and isolation of mutants of microorganisms. Corequisite or prerequisite: Biological Sciences 100. Prerequisites: Biological Sciences 99 and 194S. At the First Open Enrollment, this lab will be restricted to students who require it for completion of their degree. This enrollment restriction will be lifted at the beginning of the Second Open Enrollment Period.

M116L Molecular Biology Laboratory (4) F, W, S, Summer. Laboratory, four hours; lecture, two hours. Students perform experiments which illustrate the chemical and biological properties of nucleic acids. Emphasis is placed on recent techniques in recombinant DNA technology including gene isolation and characterization. Corequisite or prerequisite: Biological Sciences 100. Prerequisites: Biological Sciences 99 and 194S. At the First Open Enrollment, this lab will be restricted to students who require it for completion of their degree. This enrollment restriction will be lifted at the beginning of the Second Open Enrollment Period.

M118L Experimental Microbiology Laboratory (4) F, W, S, Summer. Laboratory, four hours; lecture, two hours; discussion, one hour. Introductory general microbiology designed for preprofessional biology majors. Includes microscopy, cultivation of bacteria, morphological and biochemical characterization of bacteria, microbial metabolism, growth and genetics, microorganisms and human disease, and interactions of microorganisms with the environment. Corequisite or prerequisite: Biological Sciences 100. Prerequisites: Biological Sciences 99 and 194S. At the First Open Enrollment, this lab will be restricted to students who require it for completion of their degree. This enrollment restriction will be lifted at the beginning of the Second Open Enrollment Period.

M121L Advanced Immunology Laboratory (4) S. Lecture, four hours; discussion, one hour. Emphasis is placed on learning modern techniques in immunology such as ELISAs, western blotting, immunofluorescent staining assays. Corequisite or prerequisite: Biological Sciences 100. Prerequisites: Biological Sciences 194S, M116L, and M121. Concurrent with Molecular Biology and Biochemistry 221L. At the First Open Enrollment, this lab will be restricted to students who require it for completion of their degree. This enrollment restriction will be lifted at the beginning of the Second Open Enrollment Period.

M122L Advanced Microbiology Laboratory (4) W. Laboratory, four hours; discussion, one hour. Advanced course featuring selective isolation of a wide variety of microbial types. Identification and characterization of organisms by morphological, nutritional, and biochemical approaches. Medical, industrial, and research applications. Corequisites or prerequisites: Biological Sciences 100 and either Biological Sciences M122 or M132. Prerequisite: Biological Sciences 194S. At the First Open Enrollment, this lab will be restricted to students who require it for completion of their degree. This enrollment restriction will be lifted at the beginning of the Second Open Enrollment Period.

M124L Virus Engineering Laboratory (4) S. Laboratory, four hours; discussion, one hour. An advanced laboratory for undergraduates who have completed a virology lecture class. Students learn to engineer recombinant viruses and express genes in mouse tissue. Corequisite or prerequisite: Biological Sciences 100. Prerequisites: Biological Sciences 194S, M116L, and either M124A or M124B. .At the First Open Enrollment, this lab will be restricted to students who require it for completion of their degree. This enrollment restriction will be lifted at the beginning of the Second Open Enrollment Period.

M127L Virology and Immunology Laboratory (5) S. Laboratory, four hours; lecture, one hour. Introductory laboratory course in virology and immunology designed for biology majors. Curriculum includes plasmid preparation, plasmid characterization, microscopy, cell culture, transfection and infection of cells, cell counting, plaque assays, ELISA, Western blot, mixed lymphocyte reactions. Corequisite: Biological Sciences M121 or M124A. Corequisite or prerequisite: Biological Sciences 100. Prerequisites: Biological Sciences 99, 194S, and M116L. At the First Open Enrollment, this lab will be restricted to students who require it for completion of their degree. This enrollment restriction will be lifted at the beginning of the Second Open Enrollment Period.

M130L Advanced Molecular Lab Techniques (6) W, S, Summer. Lecture, two hours; laboratory, six hours. Discovery-driven experimentation in the fields of molecular biology, biochemistry, and cell biology. Also involves other aspects of the lab experience including group discussion of results, scientific paper analysis, and student presentations. Prerequisites: Biological Sciences100 and 194S; and D111L or M114L or M116L or M118L. At the First Open Enrollment, this lab will be restricted to students who require it for completion of their degree. This enrollment restriction will be lifted at the beginning of the Second Open Enrollment Period.

N113L Neurobiology Laboratory (3) W, S. Laboratory, three hours; discussion, one hour. Corequisites or prerequisites: Biological Sciences 100 and N110. Prerequisite: Biological Sciences 194S. At the First Open Enrollment, this lab will be restricted to students who require it for completion of their degree. This enrollment restriction will be lifted at the beginning of the Second Open Enrollment Period.

UPPER-DIVISION ELECTIVES

DEVELOPMENTAL AND CELL BIOLOGY

D113 Genetics Majors Seminar (1) W. Seminar, one hour. Genetics majors attend a weekly seminar to discuss current research techniques and career opportunities in the field. Students have the opportunity to present their own independent research. Open to Genetics majors only. May be taken for credit two times.

D114 Developmental and Cell Biology Majors Seminar (1) S. Seminar, one hour. Developmental and Cell Biology majors attend a weekly seminar to discuss current research techniques and career opportunities in the field. Students have the opportunity to present their own independent research. Pass/Not Pass only. May be taken for credit two times.

D116 Human Reproduction and Development PBL Course (4) Summer. Lecture, six hours. Focuses on human reproductive biology and in utero human development. Taught in a problem-based learning (PBL) format focused on the biological, social, economic, and ethical implications of specific clinical cases. Prerequisites: Biological Sciences 93, 94, 97, 98, and 99, or equivalent.

D117 Movement and Health (4) Summer. Lecture, three hours. Mechanisms of movements of molecules within and across cell membranes, cytoskeleton and cell motility, muscle contraction, and physical exercises and mind-body practices. Chemical, electromagnetic, and vital energy, and regulatory pathways in such processes. Relevance to health, diseases, and integrative medicine. Prerequisite: Biological Sciences 99.

D121 Stem Cell Biology (4). Lecture, three hours. Introduces upper-level undergraduate students to stem cell biology. Include the basic biology of stem cells, potential applications of stem cells, and the ethical, legal, and moral issues associated with human stem cell research. Prerequisites: Biological Sciences D103 and D104.

D124 Biology of Integrative Medicine (4). Lecture, three hours. Presentation of biological principles and the latest clinical and basic research on complementary and alternative therapies (e.g., mind-body medicine, energy medicine, herbal medicine, acupuncture, manipulative therapies) and their integration with Western medicine. Lectures supplemented by demonstrations and hands-on learning sessions. Only one course from Biological Sciences D124, 9J, and 9N may be taken for credit.

D125 The Biology and Genetics of Cancer (4). Cancer is a major field in modern biology. Topics discussed include genetics, cellular oncogenes, tumor suppressor genes, and molecular targets for diagnosis and therapy. Prerequisite: Biological Sciences 99.

D129 Biotechnology and Plant Breeding (4) S. Lecture, three hours. Synopsis of conventional plant breeding techniques, their limitations, and supplementations through modern biotechnology. These new biotechnological methods include steps such as cloning, cell transformation (genetic engineering), and cell fusion. Focuses on crop improvement, the state of the art in animal and human systems, and the impact of gene technology on society. Prerequisite: Biological Sciences 94 or consent of instructor.

D130 Photomedicine (4) W. Lecture, three hours; discussion, one hour. Studies the use of optical and engineering-based systems (laser-based) for diagnosis, treating diseases, manipulation of cells and cell function. Physical, optical, and electro-optical principles are explored regarding molecular, cellular, organ, and organism applications. Prerequisites: Physics 3C or 7D, or Engineering EECS12, or consent of instructor. Same as Engineering BME135.

D136 Human Anatomy (4) F. Lecture, three hours; discussion, one hour. Presents a systems approach to the analysis of human structure. Molecular, cellular, tissue, organ, and organ system levels of structure and organization are integrated throughout. Prerequisite: Biological Sciences 99.

D137 Eukaryotic and Human Genetics (4) F. Lecture, four hours. Structure and function of genes in eukaryotes with emphasis on special problems of genetic studies in humans. Molecular methods of genetic analysis and gene transfer are discussed. Practical applications and ethical and social issues raised by genetic studies are addressed. Prerequisites: Biological Sciences 97; Biological Sciences 99 recommended.

D145 Genomics and Proteomics (4) W. Lecture, three hours. Focuses on the applications of genomics and proteomics to problems in genetics, cell, and developmental biology. Students gain a comprehensive understanding of the techniques currently used for genomics analysis and how best to apply these tools to solve research problems. Prerequisites: Biological Sciences 97, 98, 99.

D148 Development and Disease (4) S. Lecture, three hours. Development of animal embryos from a fertilized egg to a functioning organism. Topics include body-axis formation, growth and differentiation of embryonic cells, and organogenesis, with an emphasis on congenital birth defects and diseases that disrupt these processes. Prerequisite: Biological Sciences D104.

D153 Molecular and Cellular Basics of Disease (4). Lecture, three hours. Provides students with examples of how human disease is usually manifested at the cellular level. The roles of specific molecules and organelles are discussed where their roles in the disease process are understood. Prerequisite: Biological Sciences D103.

D154 Cell Biology (4) F. Lecture, three hours. An advanced, integrated view of cell biology. Topics include the cell cycle, the cytoskeleton, the extracellular matrix, signal transduction, the cellular basis of development, and the cell biology of cancer. Prerequisite: Biological Sciences D103 or 107.

D155 Systems Cell and Developmental Biology (4) W. Lecture, three hours. Introduces concepts needed to understand cell and developmental biology at the systems level, i.e., how the parts (molecules) work together to create a complex output. Emphasis on using mathematical/computational modeling to expand/modify insights provided by intuition. Concurrent with Developmental and Cell Biology 232.

D190 Topics in Developmental and Cell Biology (2 to 4) F, W, S. Lecture, two hours. Studies in selected areas of developmental and cell biology. Prerequisites: Biological Sciences D103; limited to School of Biological Sciences majors with upper-division standing. May be taken for credit three times as topics vary.

ECOLOGY AND EVOLUTIONARY BIOLOGY

E107 Seminar in Ecology and Evolutionary Biology (2) F, W, S. Seminar, one and one-half hours. Invited speakers, graduate students, and faculty present current research in ecology and evolutionary biology. Pass/Not Pass only. Open only to upper-division Ecology and Evolutionary Biology majors.

E118 Ecosystems Ecology (4) F, W, S. Lecture, three hours. A mechanistic perspective on ecosystem processes. Covers ecosystem development, element cycling, and interactions with plants and microbes. The role of ecosystems in environmental change is also addressed. Prerequisite: Chemistry 51C. Same as Earth System Science 164. Concurrent with Earth System Science 264.

E124 Infectious Disease Dynamics (4) F, W, S. Lecture, three hours. Discusses how the dynamical interactions between pathogens and the immune system can give rise to a variety of outcomes which include clearance of infection, persistent infection, escape from immune responses, and pathology. Prerequisite: Biological Sciences 96 or E106 or 97.

E127 Physiological Plant Ecology (4) F. Lecture, three hours. An examination of the interactions between plants and their environment. Emphasis on the underlying physiological mechanisms of plant function, adaptations and responses to stress, and the basis of the distribution of plants and plant assemblages across the landscape. Prerequisites: Biological Sciences E106 or Earth System Science 51 or 60A and 60C. Same as Earth System Science 168. Concurrent with Earth System Science 268.

E130 Forensic Genetics (4) S. Lecture, three hours. Covers techniques currently used for forensic identification and paternity testing. Topics include STR, Y-STR and mitochondrial DNA tests, database searches, mixtures, allelic drop out, likelihood ratios, laboratory errors and the interaction of science and the legal system. Prerequisites: Biological Sciences 93 and 94.

E135 Molecular Evolution (4) W. Lecture, three hours. Introduction to the study of evolutionary change in genes and DNA sequences. Combines study of molecular biology with the study of evolution. Molecular evolution has application to many disciplines, including molecular biology, virology, systematics, and the origin of life. Prerequisite: Biological Sciences E106.

E136 The Physiology of Human Nutrition (4) S. Lecture, three hours. Examines the biochemical basis of energy metabolism, physiological processes in digestion and uptake, and the biochemical transformation of carbohydrates, fats, and proteins in the human body. The emphasis is on expanding the students' understanding of physiology. Prerequisites: Biological Sciences 98 and E109.

E137 Genetics of Complex Traits (4) F, W, S. Lecture, three hours; discussion, one hour. Many ecologically important traits (e.g., size, age at sexual maturity) and clinical conditions are rooted in the interaction of multiple genetic loci with the environment. Theoretical and practical approaches to dissecting the genetic architecture of complex traits are explored. Prerequisites: Biological Sciences 96 or E106, and 97; Biological Sciences 7 or Mathematics 7 recommended.

E138 Comparative Animal Physiology (4) S of odd years. Lecture, three hours. Maintenance aspects of physiology: water balance; feeding and digestion; metabolism; respiration and circulation. Prerequisite: Biological Sciences E109.

E140 Evolution and the Environment (4) S. Seminar and lecture, three hours. Explores basic topics in ecology and evolutionary biology and applications to agriculture, conservation, environmental issues, and public health. Format involves discussion of scientific journal articles and other readings, with focus on learning to evaluate scientific evidence. Prerequisite or corequisite: Biological Sciences E106.

E142 Writing/Philosophy of Biology (4) F, W, S. Lecture, three hours. Philosophy of biology, e.g., scientific method in biology, the structure of evolutionary theory, teleology, ethics, and evolution. Course work includes one 4,000-word and four 1,000-word papers. Prerequisite: satisfactory completion of the lower-division writing requirement. Same as Philosophy 142 and Logic and Philosophy of Science 142.

E145 Animal Coloration and Vision (4) F. Lecture, three hours. Physiological and behavioral mechanisms of color production and vision including crypsis, mimicry, aposematism, masquerade, sexual dimorphism, and predator-prey interactions through the lens of signals, receivers, and receptors; color and polarization vision in mate choice and visual adaptations to aquatic environments. Corequisite or prerequisite: Biological Sciences E106.

E150 Conservation Biology (4) W. Lecture, three hours. Genetic and ecological issues in conservation biology, including effects of human population growth, the value of biodiversity, conservation genetics, demography, metapopulation dynamics, community and ecosystem processes, species invasions, global climate change, and reserve design and management. Prerequisite: Biological Sciences E106.

E151 Population Dynamics in Ecology, Epidemiology, and Medicine (4) S. Lecture, three hours. Explore the dynamics of populations on an ecological, epidemiological, and medical level. Considers the dynamics of competition, predation, and parasitism; the spread and control of infectious diseases; and the in vivo dynamics of viral infections and the immune system. Prerequisite: Biological Sciences 94 or E106. Concurrent with Ecology and Evolutionary Biology 251.

E153 Functional and Structural Evolutionary Genomics (4) W. Lecture and computer lab, four hours. Function and organization of genomes analyzed from an evolutionary perspective. Review of some of the most recent experimental approaches in genome analysis and comparative genomics. Relevant software to analyze DNA and expression data is used. Prerequisite: Biological Sciences 97. Recommended: Biological Sciences E135 or E168, and Biological Sciences 7 or Statistics 7/Mathematics 7. Concurrent with Ecology and Evolutionary Biology 253.

E154 Genetics and Human History (4) F. Lecture, three hours. Explores topics in human health and human history from an evolutionary perspective, with an emphasis on genetics. Topics include the relationship between genetics and human disease as an evolutionary question, and how modern genetic techniques are used to study the history of human populations. Corequisite or prerequisite: Biological Sciences E106.

E157 Comparative Vertebrate Anatomy (4) W. Lecture, three hours. Structure and evolution of the major organ systems in vertebrates, from fish to mammals. Prerequisite: Biological Sciences 94.

E160 Biology of Birds (4). Lecture, three hours. A thorough introduction to the biology of birds, covering topics ranging from avian anatomy and physiology to behavior, natural history, ecology, genetics, evolution, systematics, and conservation. Examples from both local and global avifauna. Corequisite: Biological Sciences E161L. Prerequisite: Biological Sciences 94.

E163 Environmental Microbiology (4) F. Lecture, three hours. Establishes a fundamental understanding of microbes living in the environment, including their distribution, diversity, and biochemistry, and discusses how they attribute to global biogeochemical cycles. Prerequisites: Biological Sciences E106 or Earth System Science 53 or 60A and 60C. Same as Earth System Science 170. Concurrent with Earth System Science 270.

E168 Evolution (4) S. Lecture, three hours. An integrative treatment of evolutionary biology that covers evolutionary processes, basic research methods, and the history of life. Prerequisite: Biological Sciences E106.

E170 Mechanical Physiology (4). Lecture, three hours. Explores the mechanics of animal physiology. Basic biomechanical principles are introduced and illustrated in a variety of physiological systems. Topics include the fluid and structural mechanics of muscles, skeletons, circulation, insect flight, biomaterials, and fish swimming. Prerequisite: Biological Sciences E109.

E172 Plant Diversity in a Changing World (4) S of odd years. Lecture, three hours. Investigation of planet diversity in California and throughout the world, including basic systematic concepts, an introduction to major groups of flowering plants, and the effects of global biological change on plant diversity. Prerequisite: Biological Sciences E106. Concurrent with Ecology and Evolutionary Biology 272.

E174 Behavioral Ecology (4) F, W, S. Lecture, three hours; discussion, two hours. Animal behavior as an evolutionary solution to problems encountered during an animal's life cycle. Includes a broad comparative approach to communication, social behavior, habitat selection, and food finding. Prerequisite: Biological Sciences E106 or consent of instructor.

E175 Restoration Ecology (4) F, W, S. Lecture, two hours; field work, two hours. Theoretical and practical aspects of habitat restoration and mitigation. Design, implementation, and monitoring of restoration projects in local habitats. Collection of seed and cuttings, planting and maintenance presented. Control of exotics in natural areas discussed. Environmental ethics of restoration emphasized. Prerequisite or corequisite: Biological Sciences E106.

E176 Evolution of Infectious Disease (4) W of even years. Lecture, three hours; discussion, one hour. Introduction to the major human pathogens, and the ecological and evolutionary processes affecting their impact on public health. Topics include the evolution of drug resistance, problems in vaccine development, diseases emerging from animals, and bioterrorism. Prerequisite: Biological Sciences 94.

E178 Ocean Ecology (4) W of even years. Lecture, three hours; discussion, one hour. Examines the relationships between physical processes in the ocean, biological productivity, and the exploitation of ocean resources by high-trophic-level predators, including humans. Discusses open ocean ecosystems, intertidal and benthic regions of the world ocean. Prerequisite: Biological Sciences 94.

E179 Limnology and Freshwater Biology (4) F, W, S. Lecture, three hours; discussion, one hour. Biology of freshwater environments: lakes, ponds, rivers, their biota, and the factors which influence distribution of organisms. Prerequisite: Biological Sciences 94.

E181 Conservation in the American West (4) W. Lecture, three hours. Critical examination of contemporary conservation issues in the American West, with particular attention to water in California, grazing on public lands, and species decline and extinctions. Prerequisite: Biological Sciences E106.

E182 Mediterranean Ecosystems: Biodiversity and Conservation (4) W. Lecture, three hours. Biodiversity, history of human impacts, and conservation efforts are examined in the five Mediterranean-type ecosystems. The extent of remaining natural habitat, approaches to ecological habitat restoration, control of exotic species, and predicted consequences of global climate change are described. Prerequisite or corequisite: Biological Sciences E106.

E183 Exercise Physiology (4) S. Lecture, three hours. Focus upon critical topics in the area of exercise biology using the comparative physiological approach. Specifically examine the physiological factors that limit the capacity of an organism to sustain high levels of aerobic metabolism. Prerequisites: Biological Sciences 98 and E109.

E184 Ecology and Diversity of Insects (4) W of odd years. Lecture, three hours. Insects—representing two-thirds of all species—play fundamental roles in human health, agriculture, and natural ecosystems. Topics include insect morphology, development, physiology, taxonomy, ecology, and insects in human affairs. Lecture includes interactive demonstrations and an optional weekend trip. Prerequisite: Biological Sciences E106 or consent of instructor.

E186 Population and Community Ecology (4) W. Lecture, three hours. Population structure, function, development, and evolution. Topics include population structure, population growth and regulation, metapopulations, predation, competition, species diversity, ecosystem function, macroecology, and island biogeography. Prerequisite: Biological Sciences E106.

E188 Introduction to Insect Physiology (4) W of even years. Lecture, three hours. Physiology of insects. Insect respiration, digestion, excretion, and neurobiology, including sensory systems and effectors. Prerequisite: Biological Sciences E109.

E189 Environmental Ethics (4) W. Lecture, three hours. History of evolution of environmental ethics in America. Management problems in national parks, wilderness areas, wild and scenic rivers, national forests. Contemporary and historical aspects/contributors to the field. Mitigation, endangered species, habitat restoration, biodiversity, and environmental activism. Field trips required. Prerequisite: upper-division standing.

E190 Topics in Ecology and Evolutionary Biology (2 to 4) F, W, S. Lecture, two to four hours. Studies in selected areas of ecology and evolutionary biology. Prerequisite: Biological Sciences E106. May be taken for credit three times as topics vary.

MOLECULAR BIOLOGY AND BIOCHEMISTRY

M114 Advanced Biochemistry (4) F, W, S. Lecture, three hours; discussion, one hour. Physical-chemical properties of macromolecules. Structure-function relationships in nucleic acids, protein, carbohydrates, and lipids. Integration and regulation of metabolism. Biochemistry of organs and biochemistry of diseases. Prerequisite: Biological Sciences 99.

M116 Advanced Molecular Biology (4) F, W, S. Lecture, three hours; discussion, one hour. Mechanisms of gene expression; special emphasis on regulatory events that occur in Eukaryotic organisms other than initiation of transcription. Chromatin structure and rearrangement, RNA polymerases, cis- and trans-acting elements, RNA processing, transport and stability, protein synthesis, trafficking, and turnover. Prerequisites: Biological Sciences 99, and M114L or M116L.

M119 Advanced Topics in Immunology (4) S. Lecture, one-half hour; discussion, two and one-half hours. Literature-based, interactive discussions focused on review of seminal historic and recent immunology literature. Student responsibilities include reading, critical evaluation, and discussion of manuscripts. Prerequisite: Biological Sciences M121. Microbiology and Immunology majors have first consideration for enrollment.

M120 Signal Transduction in Mammalian Cells (4) F. Lecture, three hours. Introduction to major biochemical pathways that transmit information from extracellular cues into changes in cell behavior. Focuses on kinases, phosphateses, G proteins, second messengers, and protein-protein interactions. Includes discussion of primary research articles and experimental techniques. Prerequisite: Biological Sciences D103.

M121 Immunology with Hematology (4) W. Lecture, three hours; discussion, one hour. Antibodies, antigens, antigen-antibody reactions, cells and tissues of lymphoreticular and hematopoietic systems, and individual and collective components of cell-mediated and humoral immune response. Prerequisite: Biological Sciences 98 or consent of instructor.

M122 General Microbiology (4) F, S, Summer. Lecture, three hours; discussion, one hour. Comparative metabolism of small molecules and cell structure and relationship to microbial classification. Macromolecule synthesis and regulation, sporulation, cell division, growth, and effect of antibiotics. Prerequisite: Biological Sciences 98.

M123 Introduction to Computational Biology (4) S. Lecture, three hours; laboratory, two hours. The use of theories and methods based on computer science, mathematics, and physics in molecular biology and biochemistry. Basics in biomolecular modeling. Analysis of sequence and structural data of biomolecules. Analysis of biomolecular functions. Prerequisite: Mathematics 2D or 2J or 7 or Statistics 7 or 8. Same as Computer Science 183. Concurrent with Molecular Biology and Biochemistry 223.

M124A Virology (4) F. Lecture, three hours; discussion, one hour. Replication of viruses in populations, animals, and the host cell. The effects of viral infection on populations, individuals, and specific molecular effects on the target cell. Role of viral infections in cancer and degenerative diseases. Prerequisite: Biological Sciences 99.

M124B Viral Pathogenesis and Immunity (4) W. Lecture, three hours. The mechanisms of viral pathogenesis and of host resistance to viruses are explored in detail. HIV-1 and Influenza-A are used as examples. In each case, viral replication, cytopathic effects, immune response, and viral evasion are discussed. Prerequisites: Biological Sciences M121 or M124A, or consent of instructor; Biological Sciences M122 recommended.

M125 Molecular Biology of Cancer (4) S. Lecture, three hours. Molecular mechanisms of carcinogenesis. Consideration of transformation by DNA tumor viruses, RNA tumor viruses, and chemical carcinogens. Prerequisite: Biological Sciences 99 or consent of instructor.

M133 High-Resolution Structures: NMR and X-ray (4) F of even years. Lecture, three hours. Basic principles of magnetic resonance and x-ray crystallography toward the determination of high-resolution biomolecular structures. Prerequisites: Mathematics 2B and consent of instructor. Concurrent with Molecular Biology and Biochemistry 211.

M137 Microbial Genetics (4) W. Lecture, three hours; discussion, one hour. Prerequisites: Biological Sciences 97 and 98. Recommended: concurrent enrollment in Biological Sciences 99.

M143 Human Parasitology (4) S. Lecture, three hours. Introduction to human animal-parasitic diseases including worms and protozoan infections. Prerequisite: Biological Sciences 99.

M144 Cell Organelles and Membranes (4) S. Lecture, three hours. Structure, function, and biogenesis of biological membranes and membrane-bound organelles; protein trafficking and transmembrane signaling. Prerequisite: Biological Sciences D103.

M160 Structure-Function Relationships of Integral Membrane Proteins (4) W. Lecture, three hours. Integral membrane proteins such as voltage and ligand-gated ion channels, water channels, pumps, cotransporters, and receptors (e.g., GPCRs). The emphasis is on the relationship between atomic structure and the functional properties of these proteins. Prerequisites: a grade of B or better in Biological Sciences 98 and 99. Concurrent with Molecular Biology and Biochemistry 255.

M190 Topics in Molecular Biology and Biochemistry (2 to 4) F, W, S. Lecture, two to four hours. Studies in selected areas of Molecular Biology and Biochemistry. Prerequisite: Biological Sciences 98 or consent of instructor. May be taken for credit three times as topics vary.

NEUROBIOLOGY AND BEHAVIOR

N112A-B-C Neuroscience: Fundamental Concepts and Current Applications (3-3-3) F, W, S. Lecture, three hours; seminar, one hour. In-depth exploration of the intellectual tools used to create, advance, and disseminate knowledge about the nervous system. Develops analytical, reasoning, and communication skills by exploring fundamental issues of data interpretation in cellular, molecular, systems, and behavioral analyses of brain function. Prerequisite: Biological Sciences N110.

N119 History of Neuroscience (4) F, W, S. Lecture, three hours. An overview of the conceptual and technical foundations of contemporary neuroscience from ancient times to the present. The subjects include synapses, neurons, brain organization, sensory, motor and regulatory systems, learning and memory, human brain function and dysfunction. Prerequisites: Biological Sciences 35 or N110, or Psychology and Social Behavior P115D, or Psychology 9A-B-C, or consent of instructor. Concurrent with Neurobiology and Behavior 255.

N147 Hearing and the Brain (4) F. Lecture, three hours. An overview of brain mechanisms of hearing, including perception of simple sounds, speech, and music. Begins with sound itself, and looks at processing by the ear, auditory pathways, auditory cortex, and beyond. Also auditory development, learning, and clinical issues. Prerequisite: Biological Sciences N110 or Psychology 160A. Same as Psychology 161H.

N150 Brain Dysfunction and Repair (4). Lecture, three hours. Introduction to the disruptions in brain function that underlie disorders such as Alzheimer's disease, Parkinsonism, schizophrenia, and depression, and the basis for drug therapies. The brain's ability to repair itself after damage and the pros and cons of that repair. Prerequisite: Biological Sciences N110. Open to majors only.

N152 Developmental Neurobiology (4) F. Lecture, three hours. The development of the nervous system is discussed with emphasis on the processes that underlie the appearance of complex and highly ordered neural circuits. Topics include neural induction, specification, migration and death; axon growth, and neural circuit formation. Prerequisite: Biological Sciences 93.

N153 Neuropharmacology (4) S. Lecture, three hours. Survey of neurotransmitter systems, focusing on how transmitters are made, how they interact with their receptors, and how drugs can influence these processes to alter neural function and behavior. Prerequisite: Biological Sciences N110.

N154 Molecular Neurobiology (4) F, W, S. Lecture, three hours. Nature and actions of genes and gene products that regulate the functioning of the nervous system and its interaction with muscles. Topics include: neural control of gene expression; genetics and molecular biology of neural and neuromuscular diseases; gene therapies for neural disorders. Prerequisite: Biological Sciences N110.

N155 Wiring the Developing Brain (4). Lecture, three hours; discussion, one hour. The development of the nervous system is discussed with particular emphasis on the processes that underlie the appearance of complex and highly ordered neural circuits. Basic neurodevelopmental processes are discussed and correlated with normal brain function/dysfunction. Prerequisite: Biological Sciences N110 or N152.

N156 Molecular Mechanisms of Memory (4). Lecture, three hours. Covers current topics focused on understanding the molecular mechanisms that contribute to synaptic plasticity, learning, and memory. Primary literature is used to explore the variety of molecular mechanisms underlying these processes. Prerequisite: Biological Sciences N110.

N158 Neurobiology of Learning and Memory (4). Lecture, three hours. How the brain and behavior change as a result of experience, with an emphasis on identifying the neurochemical processes through which memory is stored and the parts of the brain that are involved. Prerequisite: Biological Sciences 35 or N110. Same as Psychology 162A.

N159 Animal Behavior (4) S. Lecture, three hours. Explores why animals behave the way they do from both evolutionary and mechanistic perspectives. Considers selective pressures and evolutionary constraints that shape animal behavior and the underlying neural and hormonal mechanisms by using examples such as why dogs bark, why some birds migrate. Prerequisite: Biological Sciences N110.

N160 Language and the Brain (4) W. Lecture, three hours. Analysis of current research on the biological bases of human linguistic capacity. Development, focusing on hemispheric specialization and plasticity; localization of specific linguistic functions in adults, with emphasis on study of aphasias; relation of linguistic capacity to general cognitive capacity, considering research on retardation. Prerequisite: Biological Sciences 35 or N110, or consent of instructor. Same as Psychology 161 and Linguistics 158.

N164 Functional Neuroanatomy (4) F, W, S. Lecture, three hours. How neuroscience uses tools of many disciplines, from imaging to behavior, to develop and test hypotheses about functions of specific parts of the brain. Basic organization of nerve cells and vertebrate nervous system; methods of visualizing nerve cells; neural connections, neural activity patterns. Prerequisite: Biological Sciences N110.

N165 Brain Disorders and Behavior (4). Lecture, three hours. Examines the localization of human brain functions and the effects of neurological disorders on psychological functions such as perception, motor control, language, memory, and decision-making. Prerequisites: Psychology 7A or 9A, B, or Psychology and Social Behavior 9 or 11A, B, or Biological Sciences 35, or equivalent, or consent of instructor. Same as Psychology 160D.

N166 Introduction to Cognitive Neuroscience (4). Lecture, three hours; discussion, one hour. Introduction to the neural basis of human perceptual, motor, and cognitive abilities. Topics include sensory perception, motor control, memory, language, attention, emotion, frontal lobe function, functional brain imaging, and neuropsychological disorders. Prerequisite: Biological Sciences 35, or Psychology and Social Behavior 9 or 11A, B, or Psychology 7A or 9A, B, or consent of instructor, or equivalent. Same as Psychology 160A and Psychology and Social Behavior 192L.

N182 Vision (4). Lecture, three hours; discussion, one hour. Visual perception and the anatomy and physiology of the visual system. Topics include: the retina and the visual pathway; visual sensitivity; color vision; spatial vision; motion perception; and the development of the visual system. Same as Psychology 131A. Psychology 130A may not be taken for credit after Biological Sciences N182.

N190 Topics in Neurobiology and Behavior (2 to 4) F, W, S. Lecture, four hours. Studies in selected areas of neurobiology and behavior. Prerequisite: Biological Sciences N110. May be taken for credit three times as topics vary.

Seminars and Special Courses

191A-B Senior Seminar on Global Sustainability I, II (2-2) F, W. Students attend weekly seminar to discuss current issues in global sustainability. Weekly attendance at Global Sustainability Forum also is required. Seminar utilized to analyze forum presentations. A: Prepare bibliography. B: Prepare research proposal. In-progress grading for 191A-B, grade for sequence given upon completion of 191C. Prerequisites: senior standing, Biological Sciences 65, Environmental Analysis and Design E20, and Earth System Science 10. Same as Earth System Science 190A-B and Social Ecology 186A-B.

191C Writing/Senior Seminar on Global Sustainability III (4) S. Students attend weekly seminar to discuss current issues in global sustainability. Weekly attendance at Global Sustainability Forum also is required. Seminar utilized to analyze forum presentations and to prepare senior research paper. Prepare/write research paper under the direction of a faculty member. Prerequisites: Biological Sciences 191A-B and satisfaction of the lower-division writing requirement. Same as Earth System Science 190C and Social Ecology 186C.

192 Tutoring in Biology (2). Enrollment limited to participants in the Biological Sciences Peer Tutoring Program. Prerequisite: consent of instructor. May be repeated six times. No more than 12 units earned in this course may be counted toward the 180 units required for graduation. Satisfies no degree requirement other than contribution to the 180-unit total.

193 Research Writing for Biological Science Majors (4). Under the guidance of selected faculty in the School of Biological Sciences and a writing professional, students learn to conduct library research in the field of biology and to write scientific review papers. Prerequisite: upper-division Biological Sciences major.

194 Current Topics in Biology (1) F, W, S. A seminar designed to discuss recent research findings and experimental issues in biology. Meets once each week for one hour. Corequisite: Biological Sciences 199.

194S Safety and Ethics for Research (1) F, W, S. Introduces students to the concepts, techniques, and ethics involved in biological sciences laboratory work. Pass/Not Pass only.

H195A Honors Writing for Biological Research (4) S. Lecture, two hours; laboratory, two hours. A science writing and critical reasoning course. Work, research, and writing exercises are conducted in a computer laboratory with full Internet access to library and other information resources. Students complete a number of preliminary writing exercises and then further develop their Excellence in Research report to a full scientific senior thesis. This forms the basis for an oral defense. Prerequisites: three quarters of Biological Sciences 199 research, participation in Excellence in Research, and satisfactory completion of the lower-division writing requirement; open only to students eligible for the Honors Program.

H195B Honors Physiology (4) S. Seminar, three hours. Contemporary research problems in physiology using insects as model systems. Topics include digestion, osmoregulation, development, and neurobiology, including sensory systems and behavior. Participating students present papers in a journal club-style format and write short essays summarizing research findings. Prerequisites: limited to students in the Biological Sciences Honors Program and graduate students; consent of instructor.

H195C Honors Virus Evolution (4) S. Lecture, three hours; discussion, one hour. Viruses infect all domains of life and have had profound consequences on the development and survival of life. Course examines virus emergence and evolution in a broad context. Weekly overview lecture is followed by student presentations and essays based on contemporary literature. Prerequisite: Biological Sciences M124A or consent of instructor.

198A-B-C Directed Group Studies (1 to 5) F, W, S. Small group experimental laboratory or fieldwork performed under the influence of a faculty member. Prior to beginning group studies, each student must submit an abstract which must be filed in the Biological Sciences Student Affairs Office and renewed yearly, if applicable. A Summary Report must be submitted at the end of each quarter. May be graded In Progress. Prerequisites: Biological Sciences 194S and consent of instructor. May be taken for credit three times.

Independent Study

197A-B-C Special Study in Biological Sciences (1 to 4 per quarter) F, W, S. Tutorial, one to four hours. Library research, tutorial, and other independent projects under individual professors. Individualized instruction dealing with conceptual or theoretical problems in the biological sciences, rather than technical problems. Regularly scheduled meetings between student and faculty member and successful completion of a written report. Prerequisite: consent of instructor. An abstract form must be filed in the Biological Sciences Student Affairs Office. May be graded "IP." May be repeated for credit.

199 Independent Study in Biological Sciences Research (1 to 5 per quarter) F, W, S. Individual experimental laboratory or field research under a professor's direction. Required for participation in the Excellence in Research Program. Further information and a booklet describing many prospective projects are available in the Biological Sciences Student Affairs Office. Prerequisites: Biological Sciences 194S and consent of instructor. An abstract form must be filed in the Biological Sciences Student Affairs Office. May be repeated for credit as topics vary.